Multivariable logistic regression analysis of predictors for CM-TMA recurrence after eculizumab discontinuation
. | Odds ratio (95% CI) . | Level P value . | Overall P value . |
---|---|---|---|
Age, per 10-y decrease | 1.248 (1.024-1.523) | — | .029 |
Transplant (vs native) | 4.287 (1.428-12.866) | — | .009 |
Variant of highest pathogenicity | < .001 | ||
CFH (vs none) | 14.561 (5.659-37.469) | < .001 | |
C3 (vs none) | 9.385 (2.586-34.069) | < .001 | |
MCP/CD46 (vs none) | 6.413 (2.413-17.047) | < .001 | |
Other/variant not specified (vs none) | 2.002 (0.753-5.318) | .164 |
. | Odds ratio (95% CI) . | Level P value . | Overall P value . |
---|---|---|---|
Age, per 10-y decrease | 1.248 (1.024-1.523) | — | .029 |
Transplant (vs native) | 4.287 (1.428-12.866) | — | .009 |
Variant of highest pathogenicity | < .001 | ||
CFH (vs none) | 14.561 (5.659-37.469) | < .001 | |
C3 (vs none) | 9.385 (2.586-34.069) | < .001 | |
MCP/CD46 (vs none) | 6.413 (2.413-17.047) | < .001 | |
Other/variant not specified (vs none) | 2.002 (0.753-5.318) | .164 |