Table 2.

Summary of platelet responses to romiplostim treatment

ResponseAll patients (N = 203)
Patients who had a platelet response∗ at any time, n (%) 179 (88.2) 
Percentage of time with a platelet response,median (IQR)  
In the first 6 mo 50.0 (16.7-83.3) 
Overall treatment period 78.2 (26.7-90.4) 
Percentage of time with platelet counts ≥20 × 109/L above baseline, median (IQR) 80.1 (39.1-92.3) 
Patients who achieved a sustained platelet response, n (%)† 11 (5.4) 
Time to onset of sustained response, mean ± SD, wk 57.1 ± 36.0 
ResponseAll patients (N = 203)
Patients who had a platelet response∗ at any time, n (%) 179 (88.2) 
Percentage of time with a platelet response,median (IQR)  
In the first 6 mo 50.0 (16.7-83.3) 
Overall treatment period 78.2 (26.7-90.4) 
Percentage of time with platelet counts ≥20 × 109/L above baseline, median (IQR) 80.1 (39.1-92.3) 
Patients who achieved a sustained platelet response, n (%)† 11 (5.4) 
Time to onset of sustained response, mean ± SD, wk 57.1 ± 36.0 

SD, standard deviation.

Platelet response is defined as a platelet count ≥50 × 109/L without rescue medication use for ITP in the preceding 4 weeks.

Sustained platelet response was defined as consecutive platelet counts ≥50 × 109/L in the absence of any ITP medications for ≥24 weeks.

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