Table 1.

Pairwise multivariable analyses in the pediatric HL validation cohort

VariablePatientsPairwise multivariable analysis*
No.%HRSEP
Pairwise analysis 1      
 Model score high 31 43.7 2.4 0.4 .017 
 Stage IV 15 21.1 1.3 0.4 .468 
Pairwise analysis 2      
 Model score high 31 44.3 2.1 0.4 .055 
 Mediastinal mass >0.33, 25 35.7 1.4 0.4 .401 
Pairwise analysis 3      
 Model score high 31 43.7 3.0 0.4 .003 
 Fever 13 18.3 3.6 0.4 .002 
Pairwise analysis 4      
 Model score high 29 43.3 2.3 0.4 .028 
 Albumin <3.5 19 28.4 2.6 0.4 .010 
Pairwise analysis 5      
 Model score high 31 43.7 2.6 0.4 .010 
 Stratum SER 22 31.0 0.8 0.4 .620 
VariablePatientsPairwise multivariable analysis*
No.%HRSEP
Pairwise analysis 1      
 Model score high 31 43.7 2.4 0.4 .017 
 Stage IV 15 21.1 1.3 0.4 .468 
Pairwise analysis 2      
 Model score high 31 44.3 2.1 0.4 .055 
 Mediastinal mass >0.33, 25 35.7 1.4 0.4 .401 
Pairwise analysis 3      
 Model score high 31 43.7 3.0 0.4 .003 
 Fever 13 18.3 3.6 0.4 .002 
Pairwise analysis 4      
 Model score high 29 43.3 2.3 0.4 .028 
 Albumin <3.5 19 28.4 2.6 0.4 .010 
Pairwise analysis 5      
 Model score high 31 43.7 2.6 0.4 .010 
 Stratum SER 22 31.0 0.8 0.4 .620 

HR, hazard ratio; SE, standard error; SER, slow early responder.

*

Pairwise multivariable analyses were performed with Cox proportional hazards regression models using only patients with data available for both variables.

Mediastinal mass was unavailable for 1 patient.

Albumin measurements were unavailable for 4 patients.

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