Characteristics of patients undergoing allo-HSCT
Characteristic . | Median (range) or N (%) . |
---|---|
Age, y | 28 (8-61) |
Sex | |
Male | 24 (53) |
Female | 21 (47) |
Original disease | |
AML | 17 (38) |
ALL | 10 (22) |
MDS | 4 (9) |
NHL | 6 (13) |
AA | 3 (7) |
Others | 5 (11) |
HSCT conditioning | |
CY/TBI–based MAC | 18(40) |
BU/CY–based MAC | 6 (13) |
Other MAC | 5 (11) |
FLU/MEL–based RIC | 3 (7) |
FLU/BU–based RIC | 4 (9) |
Other RIC | 3 (7) |
Unknown | 6 (13) |
HSCT donor | |
rBM | 10 (22) |
rPB | 13 (29) |
uBM | 14 (31) |
CB | 5 (11) |
HaploBM | 3 (7) |
Years from HSCT to development of pulmonary GVHD | |
<1 y | 20 (44) |
1-3 y | 13 (29) |
>3 y | 12 (27) |
Years from HSCT to lung transplant | |
1-5 y | 19 (42) |
5-10 y | 13 (29) |
>10 y | 13 (29) |
Characteristic . | Median (range) or N (%) . |
---|---|
Age, y | 28 (8-61) |
Sex | |
Male | 24 (53) |
Female | 21 (47) |
Original disease | |
AML | 17 (38) |
ALL | 10 (22) |
MDS | 4 (9) |
NHL | 6 (13) |
AA | 3 (7) |
Others | 5 (11) |
HSCT conditioning | |
CY/TBI–based MAC | 18(40) |
BU/CY–based MAC | 6 (13) |
Other MAC | 5 (11) |
FLU/MEL–based RIC | 3 (7) |
FLU/BU–based RIC | 4 (9) |
Other RIC | 3 (7) |
Unknown | 6 (13) |
HSCT donor | |
rBM | 10 (22) |
rPB | 13 (29) |
uBM | 14 (31) |
CB | 5 (11) |
HaploBM | 3 (7) |
Years from HSCT to development of pulmonary GVHD | |
<1 y | 20 (44) |
1-3 y | 13 (29) |
>3 y | 12 (27) |
Years from HSCT to lung transplant | |
1-5 y | 19 (42) |
5-10 y | 13 (29) |
>10 y | 13 (29) |
AA, aplastic anemia; AML, acute myeloid leukemia; ALL, acute lymphoid leukemia; BM, bone marrow; BU, busulfan; CB, cord blood; FLU, fludarabine; Haplo, haploidentical; MAC, myeloablative conditioning; MDS, myelodysplastic syndrome; MEL, melphalan; NHL, non-Hodgkin lymphoma; PB, peripheral blood; r, related; RIC, reduced-intensity conditioning; u, unrelated.