Table 1. Demographic and clinical... | American Society of Hematology

Table 1.

Demographic and clinical characteristics and sequencing analysis of patients

Patient ID	Age	Sex	Dx	IGHV	Cytogenetic abnormalities∗	Paired LN–PB			LN
Patient ID	Age	Sex	Dx	IGHV	Cytogenetic abnormalities∗	RNA-seq (CD19⁺)	scRNA-seq	WES (CD19⁺)	RNA-seq
CLL-C01	61	F	CLL	U	Tri 12	Yes	No	Yes	Yes
CLL-C02	60	F	CLL	M	Del 11q	Yes	No	No	Yes
CLL-C03	60	M	CLL	M	Del 13q	Yes	Yes	No	Yes
CLL-C04	51	M	CLL	U	Del 11q	Yes	No	No	Yes
CLL-C05	57	M	CLL	M	Del 11q	Yes	No	Yes	Yes
CLL-C06	58	M	CLL	U	None	Yes	No	No	Yes
CLL-C07	61	F	CLL	U	None	Yes	No	No	Yes
CLL-C08	59	F	CLL	U	Del 11q	Yes	No	Yes	Yes
CLL-C11	67	F	CLL	M	Del 17p	Yes	Yes	No	Yes
CLL-C13	68	F	CLL	U	Tri 12	Yes	No	No	Yes
CLL-C14	55	F	CLL	U	Del 13q	Yes	No	Yes	Yes
CLL-C24	52	M	CLL	U	Del 17p	Yes	Yes	Yes	Yes
CLL-C25	53	M	CLL	U	Del 13q	Yes	No	No	Yes
CLL-C30	43	M	CLL	U	Del 17p	Yes	No	Yes	Yes
CLL-C31	48	M	CLL	U	Del 17p	Yes	No	No	Yes
CLL-C32	48	M	CLL	U	Del 13q	Yes	No	Yes	Yes
CLL-C33	50	M	CLL	U	Del 11q	Yes	Yes	Yes	Yes
CLL-C34	49	F	CLL	M	Del 13q	Yes	No	Yes	Yes
CLL-C35	60	F	CLL	U	Del 17p	Yes	No	Yes	Yes
CLL-C36	57	F	CLL	U	Del 13q	Yes	No	No	Yes
CLL-C37	73	M	CLL	M	Del 11q	Yes	No	No	Yes
CLL-C39	73	F	SLL	N/A	Tri 12	No	No	No	Yes
CLL-C41	75	M	CLL	U	Del 11q	Yes	No	Yes	Yes
CLL-C42	55	F	SLL	M	Tri 12	No	No	No	Yes
CLL-C43	55	F	CLL	U	Tri 12	Yes	No	Yes	Yes
CLL-C44	47	M	CLL	M	Del 17p	Yes	Yes	No	Yes
CLL-C45	56	F	CLL	M	Del 13q	Yes	No	Yes	Yes
CLL-C46	67	M	CLL	U	Del 13q	Yes	No	Yes	Yes
CLL-C47	59	F	SLL	U	Tri 12	Yes	No	No	Yes
CLL-C49	69	F	CLL	U	Del 17p	Yes	No	No	Yes
CLL-C51	75	M	SLL	M	Tri 12	No	No	No	Yes
CLL-C53	71	F	SLL	M	Tri 12	No	No	No	Yes
CLL-C55	66	M	SLL	U	None	No	No	No	Yes

Patient ID	Age	Sex	Dx	IGHV	Cytogenetic abnormalities∗	Paired LN–PB			LN
Patient ID	Age	Sex	Dx	IGHV	Cytogenetic abnormalities∗	RNA-seq (CD19⁺)	scRNA-seq	WES (CD19⁺)	RNA-seq
CLL-C01	61	F	CLL	U	Tri 12	Yes	No	Yes	Yes
CLL-C02	60	F	CLL	M	Del 11q	Yes	No	No	Yes
CLL-C03	60	M	CLL	M	Del 13q	Yes	Yes	No	Yes
CLL-C04	51	M	CLL	U	Del 11q	Yes	No	No	Yes
CLL-C05	57	M	CLL	M	Del 11q	Yes	No	Yes	Yes
CLL-C06	58	M	CLL	U	None	Yes	No	No	Yes
CLL-C07	61	F	CLL	U	None	Yes	No	No	Yes
CLL-C08	59	F	CLL	U	Del 11q	Yes	No	Yes	Yes
CLL-C11	67	F	CLL	M	Del 17p	Yes	Yes	No	Yes
CLL-C13	68	F	CLL	U	Tri 12	Yes	No	No	Yes
CLL-C14	55	F	CLL	U	Del 13q	Yes	No	Yes	Yes
CLL-C24	52	M	CLL	U	Del 17p	Yes	Yes	Yes	Yes
CLL-C25	53	M	CLL	U	Del 13q	Yes	No	No	Yes
CLL-C30	43	M	CLL	U	Del 17p	Yes	No	Yes	Yes
CLL-C31	48	M	CLL	U	Del 17p	Yes	No	No	Yes
CLL-C32	48	M	CLL	U	Del 13q	Yes	No	Yes	Yes
CLL-C33	50	M	CLL	U	Del 11q	Yes	Yes	Yes	Yes
CLL-C34	49	F	CLL	M	Del 13q	Yes	No	Yes	Yes
CLL-C35	60	F	CLL	U	Del 17p	Yes	No	Yes	Yes
CLL-C36	57	F	CLL	U	Del 13q	Yes	No	No	Yes
CLL-C37	73	M	CLL	M	Del 11q	Yes	No	No	Yes
CLL-C39	73	F	SLL	N/A	Tri 12	No	No	No	Yes
CLL-C41	75	M	CLL	U	Del 11q	Yes	No	Yes	Yes
CLL-C42	55	F	SLL	M	Tri 12	No	No	No	Yes
CLL-C43	55	F	CLL	U	Tri 12	Yes	No	Yes	Yes
CLL-C44	47	M	CLL	M	Del 17p	Yes	Yes	No	Yes
CLL-C45	56	F	CLL	M	Del 13q	Yes	No	Yes	Yes
CLL-C46	67	M	CLL	U	Del 13q	Yes	No	Yes	Yes
CLL-C47	59	F	SLL	U	Tri 12	Yes	No	No	Yes
CLL-C49	69	F	CLL	U	Del 17p	Yes	No	No	Yes
CLL-C51	75	M	SLL	M	Tri 12	No	No	No	Yes
CLL-C53	71	F	SLL	M	Tri 12	No	No	No	Yes
CLL-C55	66	M	SLL	U	None	No	No	No	Yes

Dx, diagnosis; IGHV, immunoglobulin heavy-chain gene; M, mutated; sc, single-cell; U, unmutated.

By fluorescent in situ hybridization and according to hierarchal classification (Döhner et al 2000).