Table 3.

Recommended laboratory tests for chronic wAIHA

CBC with differentialFolate level
Reticulocyte count Erythropoietin levela 
Review blood smear Serum protein electrophoresis 
Haptoglobin ANA, rheumatoid factor 
Bilirubin (direct/total) Flow cytometry for clonal B cellsa 
LDH level Chest/abdomen/pelvic CT scan 
Coombs test and eluate assessment (Bone marrow examination)b 
Fe/total iron-binding capacity/ferritin Prothrombin fragment 1.2a 
B12 level D-dimer 
CBC with differentialFolate level
Reticulocyte count Erythropoietin levela 
Review blood smear Serum protein electrophoresis 
Haptoglobin ANA, rheumatoid factor 
Bilirubin (direct/total) Flow cytometry for clonal B cellsa 
LDH level Chest/abdomen/pelvic CT scan 
Coombs test and eluate assessment (Bone marrow examination)b 
Fe/total iron-binding capacity/ferritin Prothrombin fragment 1.2a 
B12 level D-dimer 
a

If testing available.

b

In certain situations (see text).

ANA, antinuclear antibody; CT, computed tomographic.

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