Causes of chronic wAIHA
| Idiopathic: ~45% |
| Malignancies: LPDs: ~24% |
| 11% of CLL patients |
| Even higher after fludarabine treatment |
| Immune disorders: ~25% |
| Immune deficiency disorders (common variable immune deficiency) |
| Autoimmune disorders (systemic lupus, ulcerative colitis) |
| ~10% of patients with systemic lupus |
| ITP patients (Evans syndrome) |
| Others: ~5% |
| Viral infection (usually kids) |
| Drugs (huge number) |
| Idiopathic: ~45% |
| Malignancies: LPDs: ~24% |
| 11% of CLL patients |
| Even higher after fludarabine treatment |
| Immune disorders: ~25% |
| Immune deficiency disorders (common variable immune deficiency) |
| Autoimmune disorders (systemic lupus, ulcerative colitis) |
| ~10% of patients with systemic lupus |
| ITP patients (Evans syndrome) |
| Others: ~5% |
| Viral infection (usually kids) |
| Drugs (huge number) |
Data reproduced with permission from Hansen et al12 and Tranekær, Hansen, and Frederiksen.14