Table 2.

Preconception screening and optimization of complications in SCD

Chronic complicationsAction to be taken
Renal disease and hypertension Blood pressure, creatinine, and urinary protein 
Pulmonary hypertension Echocardiography if not done within a year or if symptomatic. Any anomalies should be discussed with a cardiologist. 
Chronic sickle lung disease Oxygen saturation in all women. Sleep studies and lung function tests where necessary. 
Avascular necrosis Review hip complications, which may worsen during pregnancy. 
Stroke If history of previous stroke, consider the role of transfusion therapy during pregnancy if not already on it. 
Chronic pain Women on long-term opioids should be referred to a chronic pain clinic for assessment and managed by a pain specialist. 
Chronic complicationsAction to be taken
Renal disease and hypertension Blood pressure, creatinine, and urinary protein 
Pulmonary hypertension Echocardiography if not done within a year or if symptomatic. Any anomalies should be discussed with a cardiologist. 
Chronic sickle lung disease Oxygen saturation in all women. Sleep studies and lung function tests where necessary. 
Avascular necrosis Review hip complications, which may worsen during pregnancy. 
Stroke If history of previous stroke, consider the role of transfusion therapy during pregnancy if not already on it. 
Chronic pain Women on long-term opioids should be referred to a chronic pain clinic for assessment and managed by a pain specialist. 
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