Table 2. Coagulation parameter and... | American Society of Hematology

Table 2.

Coagulation parameter and platelet count thresholds prior to high-bleeding-risk procedures in patients with cirrhosis

	EASL 2022⁵³	ISTH 2021⁵²	AASLD 2021⁵¹	AGA 2021⁵⁰	ACG 2020⁴⁹	SIR 2019⁴⁸
INR	Do not correct	Do not evaluate routinely	Do not correct	Do not evaluate routinely	Do not correct	INR ≥2.5
Platelet count	Do not correct	Do not correct	Do not correct	Do not evaluate routinely	≥50 000/µL	≥30 000/µL
Fibrinogen	Do not correct	Do not evaluate routinely	Do not correct	Do not evaluate routinely	No specific recommendation	≥1 g/L
Viscoelastic assay	Do not use routinely	Do not use routinely	Do not use routinely	No recommendation	May be useful	No specific recommendation

	EASL 2022⁵³	ISTH 2021⁵²	AASLD 2021⁵¹	AGA 2021⁵⁰	ACG 2020⁴⁹	SIR 2019⁴⁸
INR	Do not correct	Do not evaluate routinely	Do not correct	Do not evaluate routinely	Do not correct	INR ≥2.5
Platelet count	Do not correct	Do not correct	Do not correct	Do not evaluate routinely	≥50 000/µL	≥30 000/µL
Fibrinogen	Do not correct	Do not evaluate routinely	Do not correct	Do not evaluate routinely	No specific recommendation	≥1 g/L
Viscoelastic assay	Do not use routinely	Do not use routinely	Do not use routinely	No recommendation	May be useful	No specific recommendation

AASLD, American Association for the Study of Liver Diseases; ACG, American College of Gastroenterology; AGA, American Gastroenterological Association; EASL, European Association for the Study of the Liver; ISTH, International Society on Thrombosis and Haemostasis; SIR, Society of Interventional Radiology.

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