Adverse events
| System organ class . | Severity . | Type 2 VWD (N = 5), n (%) m . |
|---|---|---|
| Patients with at least one event | Mild | 2 (40.0) 3 |
| Moderate | 2 (40.0) 5 | |
| Blood and lymphatic system disorders | Moderate | 1 (20.0) 1 |
| Lymphadenopathy | Moderate | 1 (20.0) 1 |
| Cardiac disorders | Moderate | 1 (20.0) 1 |
| Tachycardia | Moderate | 1 (20.0) 1 |
| Gastrointestinal disorders | Mild | 2 (40.0) 3 |
| Moderate | 1 (20.0) 2 | |
| Diarrhea | Mild | 1 (20.0) 1 |
| Dyspepsia | Mild | 1 (20.0) 1 |
| Gastrointestinal hemorrhage | Moderate | 1 (20.0) 2 |
| Nausea | Mild | 1 (20.0) 1 |
| Moderate | 1 (20.0) 1 | |
| Urinary tract infection | Moderate | 1 (20.0) 1 |
| System organ class . | Severity . | Type 2 VWD (N = 5), n (%) m . |
|---|---|---|
| Patients with at least one event | Mild | 2 (40.0) 3 |
| Moderate | 2 (40.0) 5 | |
| Blood and lymphatic system disorders | Moderate | 1 (20.0) 1 |
| Lymphadenopathy | Moderate | 1 (20.0) 1 |
| Cardiac disorders | Moderate | 1 (20.0) 1 |
| Tachycardia | Moderate | 1 (20.0) 1 |
| Gastrointestinal disorders | Mild | 2 (40.0) 3 |
| Moderate | 1 (20.0) 2 | |
| Diarrhea | Mild | 1 (20.0) 1 |
| Dyspepsia | Mild | 1 (20.0) 1 |
| Gastrointestinal hemorrhage | Moderate | 1 (20.0) 2 |
| Nausea | Mild | 1 (20.0) 1 |
| Moderate | 1 (20.0) 1 | |
| Urinary tract infection | Moderate | 1 (20.0) 1 |
Percentage is calculated as the number of patients with an event divided by N (N-number of patients in the study; n - number of patients with events, m - number of events).