Table 27.
B-ALL 
 B-ALL with recurrent genetic abnormalities 
 B-ALLwith t(9;22)(q34.1;q11.2)/BCR::ABL1 
   with lymphoid only involvement 
   with multilineage involvement 
 B-ALLwith t(v;11q23.3)/KMT2A rearranged 
 B-ALL with t(12;21)(p13.2;q22.1)/ETV6::RUNX1 
 B-ALL, hyperdiploid 
 B-ALL, low hypodiploid 
 B-ALL, near haploid 
 B-ALL with t(5;14)(q31.1;q32.3)/IL3::IGH 
 B-ALL with t(1;19)(q23.3;p13.3)/TCF3::PBX1 
 B-ALL, BCR::ABL1–like, ABL-1 class rearranged 
 B-ALL, BCR::ABL1–like, JAK-STAT activated 
 B-ALL, BCR::ABL1–like, NOS 
 B-ALL with iAMP21 
 B-ALL with MYC rearrangement 
 B-ALL with DUX4 rearrangement 
 B-ALL with MEF2D rearrangement 
 B-ALL with ZNF384(362) rearrangement 
 B-ALL with NUTM1 rearrangement 
 B-ALL with HLF rearrangement 
 B-ALL with UBTF::ATXN7L3/PAN3,CDX2 (“CDX2/UBTF”) 
 B-ALL with mutated IKZF1 N159Y 
 B-ALLwith mutated PAX5 P80R 
  Provisional entity: B-ALL, ETV6::RUNX1-like 
  Provisional entity: B-ALL, with PAX5 alteration 
  Provisional entity: B-ALL, with mutated ZEB2 (p.H1038R)/IGH::CEBPE 
  Provisional entity: B-ALL, ZNF384 rearranged-like 
  Provisional entity: B-ALL, KMT2A rearranged-like 
 B-ALL, NOS 
T-ALL 
 Early T-cell precursor ALLwith BCL11B rearrangement 
 Early T-cell precursor ALL, NOS 
 T-ALL, NOS 
  Provisional entities (see supplemental Table 7) 
Provisional entity: natural killer cell ALL 
B-ALL 
 B-ALL with recurrent genetic abnormalities 
 B-ALLwith t(9;22)(q34.1;q11.2)/BCR::ABL1 
   with lymphoid only involvement 
   with multilineage involvement 
 B-ALLwith t(v;11q23.3)/KMT2A rearranged 
 B-ALL with t(12;21)(p13.2;q22.1)/ETV6::RUNX1 
 B-ALL, hyperdiploid 
 B-ALL, low hypodiploid 
 B-ALL, near haploid 
 B-ALL with t(5;14)(q31.1;q32.3)/IL3::IGH 
 B-ALL with t(1;19)(q23.3;p13.3)/TCF3::PBX1 
 B-ALL, BCR::ABL1–like, ABL-1 class rearranged 
 B-ALL, BCR::ABL1–like, JAK-STAT activated 
 B-ALL, BCR::ABL1–like, NOS 
 B-ALL with iAMP21 
 B-ALL with MYC rearrangement 
 B-ALL with DUX4 rearrangement 
 B-ALL with MEF2D rearrangement 
 B-ALL with ZNF384(362) rearrangement 
 B-ALL with NUTM1 rearrangement 
 B-ALL with HLF rearrangement 
 B-ALL with UBTF::ATXN7L3/PAN3,CDX2 (“CDX2/UBTF”) 
 B-ALL with mutated IKZF1 N159Y 
 B-ALLwith mutated PAX5 P80R 
  Provisional entity: B-ALL, ETV6::RUNX1-like 
  Provisional entity: B-ALL, with PAX5 alteration 
  Provisional entity: B-ALL, with mutated ZEB2 (p.H1038R)/IGH::CEBPE 
  Provisional entity: B-ALL, ZNF384 rearranged-like 
  Provisional entity: B-ALL, KMT2A rearranged-like 
 B-ALL, NOS 
T-ALL 
 Early T-cell precursor ALLwith BCL11B rearrangement 
 Early T-cell precursor ALL, NOS 
 T-ALL, NOS 
  Provisional entities (see supplemental Table 7) 
Provisional entity: natural killer cell ALL