Modulators of the ITI outcome
| Current characteristics for standard ITI in HA inhibitor patients . | ||
|---|---|---|
| Risk factor . | Good . | Poor . |
| Inhibitor titer before ITI | <10 BU/mL | >10 BU/mL |
| Peak inhibitor titer during ITI | <200 BU/mL | >200 BU/mL |
| Elapse time between inhibitor and initiation of ITI | <5 | >5 |
| Age at the time of ITI initiation, y | <8 | >8 |
| Interruption ITI (catheter-related complications and noncompliance) | <2 wk | >2 wk |
| Success rates | 60-70% | Variable |
| IST | No | Yes |
| Hypothetical assessment for ITI for adult patients coupled with IST | ||
| Inhibitor titer | <10 BU/mL | >10 BU/mL |
| Previous attempts for ITI | No | Failure |
| Current characteristics for standard ITI in HA inhibitor patients . | ||
|---|---|---|
| Risk factor . | Good . | Poor . |
| Inhibitor titer before ITI | <10 BU/mL | >10 BU/mL |
| Peak inhibitor titer during ITI | <200 BU/mL | >200 BU/mL |
| Elapse time between inhibitor and initiation of ITI | <5 | >5 |
| Age at the time of ITI initiation, y | <8 | >8 |
| Interruption ITI (catheter-related complications and noncompliance) | <2 wk | >2 wk |
| Success rates | 60-70% | Variable |
| IST | No | Yes |
| Hypothetical assessment for ITI for adult patients coupled with IST | ||
| Inhibitor titer | <10 BU/mL | >10 BU/mL |
| Previous attempts for ITI | No | Failure |