Table 2. Peptides containing shared HLA... | American Society of Hematology

Table 2.

Peptides containing shared HLA class I and class II epitopes eliciting CTL responses

No.	Epitope	Presenting HLA alleles	CTL line responding (n)	Immunodominant response (class I/class II)	% CD8⁺ IFN-γ⁺ CTLs		% CD4⁺ IFN-γ⁺ CTLs
No.	Epitope	Presenting HLA alleles	CTL line responding (n)	Immunodominant response (class I/class II)	Maximum	Range	Maximum	Range
1	AGILARNLVPMVATV (489-503)	A0201 DRB1 0401 DRB1 0402 DRB1 0404	5	Class I (A0201)	61.4	12-61.4	10.7	1.3-10.7
2	QPFMRPHERNGFTVL (261-275)	B0702 B0801 DRB1 0301 DRB1 1501	6 B7/DR15 = 3 B8/DR03 = 3	Class I (B0702, B0801)	44.7	15.7-44.7	8.7	3-8.7
3	PQYSEHPTFTSQYRI (361-375)	A0101 B801 DRB1 0301	2	Class I (A0101, B0801)	29.2	11.2-29.2	1.2	0.5-1.2
4	DVEEDLTMTRNPQPF (249-263)	B0801 DRB1 0301	2	Codominant class I and class II	14	9-14	6.5	4-6.5

No.	Epitope	Presenting HLA alleles	CTL line responding (n)	Immunodominant response (class I/class II)	% CD8⁺ IFN-γ⁺ CTLs		% CD4⁺ IFN-γ⁺ CTLs
No.	Epitope	Presenting HLA alleles	CTL line responding (n)	Immunodominant response (class I/class II)	Maximum	Range	Maximum	Range
1	AGILARNLVPMVATV (489-503)	A0201 DRB1 0401 DRB1 0402 DRB1 0404	5	Class I (A0201)	61.4	12-61.4	10.7	1.3-10.7
2	QPFMRPHERNGFTVL (261-275)	B0702 B0801 DRB1 0301 DRB1 1501	6 B7/DR15 = 3 B8/DR03 = 3	Class I (B0702, B0801)	44.7	15.7-44.7	8.7	3-8.7
3	PQYSEHPTFTSQYRI (361-375)	A0101 B801 DRB1 0301	2	Class I (A0101, B0801)	29.2	11.2-29.2	1.2	0.5-1.2
4	DVEEDLTMTRNPQPF (249-263)	B0801 DRB1 0301	2	Codominant class I and class II	14	9-14	6.5	4-6.5