Table 1.

Baseline characteristics

CharacteristicsCAR T-cell patients N = 280
Demographics  
 Age, median (range) 64 (19-82) 
 Sex n (%)  
  Male 185 (66) 
  Female 95 (34) 
Underlying disease, n (%)  
 Diffuse large B-cell lymphoma 158 (56) 
 Transformed follicular lymphoma 57 (20) 
 High-grade B-cell lymphoma 13 (5) 
 Transformed marginal cell lymphoma 10 (4) 
 Primary mediastinal B-cell lymphoma 10 (4) 
 Follicular lymphoma 9 (3) 
 Mantle cell lymphoma 8 (3) 
 Other non-Hodgkin lymphomas* 8 (3) 
 Transformed chronic lymphocytic leukemia 7 (2.5) 
 Prior lines of chemotherapy, median (range) 3 (2-10) 
Prior HCT, n (%)  
 Allogeneic 9 (3) 
 Autologous 82 (29) 
CAR T-cell product, n (%)  
 Axicabtagene ciloleucel 244 (87) 
 Tisagenlecleucel 22 (8) 
 Brexucabtagene autoleucel 8 (3) 
 Lisocabtagene maraleucel 6 (2) 
CharacteristicsCAR T-cell patients N = 280
Demographics  
 Age, median (range) 64 (19-82) 
 Sex n (%)  
  Male 185 (66) 
  Female 95 (34) 
Underlying disease, n (%)  
 Diffuse large B-cell lymphoma 158 (56) 
 Transformed follicular lymphoma 57 (20) 
 High-grade B-cell lymphoma 13 (5) 
 Transformed marginal cell lymphoma 10 (4) 
 Primary mediastinal B-cell lymphoma 10 (4) 
 Follicular lymphoma 9 (3) 
 Mantle cell lymphoma 8 (3) 
 Other non-Hodgkin lymphomas* 8 (3) 
 Transformed chronic lymphocytic leukemia 7 (2.5) 
 Prior lines of chemotherapy, median (range) 3 (2-10) 
Prior HCT, n (%)  
 Allogeneic 9 (3) 
 Autologous 82 (29) 
CAR T-cell product, n (%)  
 Axicabtagene ciloleucel 244 (87) 
 Tisagenlecleucel 22 (8) 
 Brexucabtagene autoleucel 8 (3) 
 Lisocabtagene maraleucel 6 (2) 
*

Other non-Hodgkin lymphomas: T-cell histiocytic rich diffuse B-cell lymphoma (n = 3); transformed follicular lymphoma and CLL (n = 1); gray-zone lymphoma (n = 2); transformed lymphoma not otherwise specified (n = 1); Burkitt and large B-cell lymphoma mixed phenotype (n = 1).

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