Patient characteristics at the onset of second-line treatment (N = 216)
| Characteristic . | n (%) . |
|---|---|
| Prednisone-equivalent steroid dose immediately before second-line treatment | |
| | 24 (11) |
| | 64 (30) |
| | 128 (59) |
| Less than 14 d from transplant to first treatment | 45 (21) |
| Less than 14 d from first treatment to second treatment | 67 (31) |
| Bilirubin (mg/dL) at time of second-line treatment | |
| | 124 (57) |
| 1.0-1.9 | 64 (30) |
| 2.0-3.9 | 16 (7) |
| | 12 (6) |
| Albumin (g/dL) | |
| | 15 (7) |
| 3.0-3.9 | 80 (37) |
| 2.0-2.9 | 92 (43) |
| 1.0-1.9 | 29 (13) |
| Any diarrhea | 135 (63) |
| No abdominal pain, no stage 4 gut | 121 (56) |
| Any abdominal pain, no stage 4 gut | 52 (24) |
| No abdominal pain, stage 4 gut | 2 (1) |
| Any abdominal pain, stage 4 gut | 41 (19) |
| Overt gastrointestinal hemorrhage | 9 (4) |
| Stage 4 gut GVHD (severe abdominal pain or overt hemorrhage) | 98 (45) |
| Rash | |
| Stage 1 | 10 (5) |
| Stage 2 | 23 (11) |
| Stage 3 | 61 (28) |
| Stage 4 | 4 (2) |
| Presence of fever | 13 (6) |
| Presence of active infection | 44 (20) |
| Characteristic . | n (%) . |
|---|---|
| Prednisone-equivalent steroid dose immediately before second-line treatment | |
| | 24 (11) |
| | 64 (30) |
| | 128 (59) |
| Less than 14 d from transplant to first treatment | 45 (21) |
| Less than 14 d from first treatment to second treatment | 67 (31) |
| Bilirubin (mg/dL) at time of second-line treatment | |
| | 124 (57) |
| 1.0-1.9 | 64 (30) |
| 2.0-3.9 | 16 (7) |
| | 12 (6) |
| Albumin (g/dL) | |
| | 15 (7) |
| 3.0-3.9 | 80 (37) |
| 2.0-2.9 | 92 (43) |
| 1.0-1.9 | 29 (13) |
| Any diarrhea | 135 (63) |
| No abdominal pain, no stage 4 gut | 121 (56) |
| Any abdominal pain, no stage 4 gut | 52 (24) |
| No abdominal pain, stage 4 gut | 2 (1) |
| Any abdominal pain, stage 4 gut | 41 (19) |
| Overt gastrointestinal hemorrhage | 9 (4) |
| Stage 4 gut GVHD (severe abdominal pain or overt hemorrhage) | 98 (45) |
| Rash | |
| Stage 1 | 10 (5) |
| Stage 2 | 23 (11) |
| Stage 3 | 61 (28) |
| Stage 4 | 4 (2) |
| Presence of fever | 13 (6) |
| Presence of active infection | 44 (20) |