RHD/RHCE blood group phenotype frequency prevalence in ASPREE and 1KGP3 samples compared with previously reported data
| Blood group gene . | Predicted phenotype . | RBCeq prediction . | Previously published53 . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ASPREE (n = 2796) . | AFR (n = 661) . | AMR (n = 347) . | EUR (n = 503) . | EAS (n = 504) . | SAS (n = 489) . | Caucasians . | Africans . | Asian . | ||
| RHD | DD | 83.09 | 96.52 | 93.95 | 83.9 | 99.8 | 94.48 | 85.00 | 92.00 | 99.00 |
| RHD | D− | 16.92 | 3.48 | 6.05 | 16.10 | 0.20 | 5.52 | 15.00 | 8.00 | 1.00 |
| RHD | DIII type 4 | 0.07 (Two heterozygous call) | 2.87 (Four homozygous and 15 heterozygous) | — | — | — | — | — | — | — |
| RHD | DUC2 | 0.07 | — | 0.30 (Two heterozygous call) | — | — | — | — | — | — |
| RHCE | C+ | 61.87 | 53.10 | 80.11 | 71.57 | 95.833 | 88.13 | 68 | 27 | 93 |
| RHCE | c+ | 81.93 | 98.48 | 74.63 | 79.52 | 45.43 | 55.01 | 80 | 96 | 47 |
| RHCE | E ce | 25.04 | 13.16 | 10.09 | 24.25 | 1.19 | 9.41 | 10.00 | 4.00 | 30.00 |
| RHCE | C E c e | 26.18 | 17.39 | 47.83 | 28.43 | 62.10 | 22.90 | 10.00 | NA | NA |
| RHCE | C partial c Partial e | — | 0.61 | — | — | — | — | NA | NA | NA |
| RHCE | C partial ec | — | 0.90 | — | — | — | — | NA | NA | NA |
| RHCE | Cw partial C e MAR− | — | — | — | 0.20 | — | — | NA | 19.00 | 3.00 |
| RHCE | Partial c Partial e | — | 4.68 | — | — | — | — | NA | NA | NA |
| RHCE | Partial e c | — | 6.80 | — | — | — | — | NA | NA | NA |
| Blood group gene . | Predicted phenotype . | RBCeq prediction . | Previously published53 . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ASPREE (n = 2796) . | AFR (n = 661) . | AMR (n = 347) . | EUR (n = 503) . | EAS (n = 504) . | SAS (n = 489) . | Caucasians . | Africans . | Asian . | ||
| RHD | DD | 83.09 | 96.52 | 93.95 | 83.9 | 99.8 | 94.48 | 85.00 | 92.00 | 99.00 |
| RHD | D− | 16.92 | 3.48 | 6.05 | 16.10 | 0.20 | 5.52 | 15.00 | 8.00 | 1.00 |
| RHD | DIII type 4 | 0.07 (Two heterozygous call) | 2.87 (Four homozygous and 15 heterozygous) | — | — | — | — | — | — | — |
| RHD | DUC2 | 0.07 | — | 0.30 (Two heterozygous call) | — | — | — | — | — | — |
| RHCE | C+ | 61.87 | 53.10 | 80.11 | 71.57 | 95.833 | 88.13 | 68 | 27 | 93 |
| RHCE | c+ | 81.93 | 98.48 | 74.63 | 79.52 | 45.43 | 55.01 | 80 | 96 | 47 |
| RHCE | E ce | 25.04 | 13.16 | 10.09 | 24.25 | 1.19 | 9.41 | 10.00 | 4.00 | 30.00 |
| RHCE | C E c e | 26.18 | 17.39 | 47.83 | 28.43 | 62.10 | 22.90 | 10.00 | NA | NA |
| RHCE | C partial c Partial e | — | 0.61 | — | — | — | — | NA | NA | NA |
| RHCE | C partial ec | — | 0.90 | — | — | — | — | NA | NA | NA |
| RHCE | Cw partial C e MAR− | — | — | — | 0.20 | — | — | NA | 19.00 | 3.00 |
| RHCE | Partial c Partial e | — | 4.68 | — | — | — | — | NA | NA | NA |
| RHCE | Partial e c | — | 6.80 | — | — | — | — | NA | NA | NA |
AFR, African; AMR, American; EAS, East Asian; EUR, European; NA, the population-level frequency was not available in the literature; SAS, South Asian.