Point estimates of primary and secondary clinical outcomes
| Variable . | ATG group (95% CI) . | PTCy group (95% CI) . | P . |
|---|---|---|---|
| GRFS | |||
| 1 y, total | 0.16 (0.08-0.31) | 0.54 (0.44-0.66) | <.001 |
| 1 y, BM only | 0.08 (0.01-0.54) | 0.61 (0.48-0.78) | |
| 1 y, PB only | 0.19 (0.09-0.38) | 0.47 (0.34-0.66) | |
| OS | <.001 | ||
| 1 y | 0.45 (0.32-0.62) | 0.75 (0.66-0.85) | |
| 2 y | 0.29 (0.18-0.46) | 0.66 (0.56-0.78) | |
| Event-free survival | <.001 | ||
| 1 y | 0.38 (0.26-0.55) | 0.69 (0.59-0.80) | |
| 2 y | 0.27 (0.17-0.44) | 0.63 (0.53-0.75) | |
| Relapse | .3 | ||
| 1 y | 0.24 (0.13-0.38) | 0.16 (0.09-0.25) | |
| 2 y | 0.26 (0.15-0.4) | 0.19 (0.11-0.29) | |
| NRM | <.001 | ||
| 1 y | 0.38 (0.23-0.52) | 0.16 (0.09-0.25) | |
| 2 y | 0.47 (0.31-0.60) | 0.19 (0.11-0.28) | |
| Acute GVHD (grades 3-4) | |||
| 180 d, total | 0.31 (0.18-0.45) | 0.15 (0.08-0.23) | .03 |
| 180 d, BM only | 0.25 (0.05-0.52) | 0.10 (0.03-0.21) | |
| 180 d, PB only | 0.33 (0.17-0.49) | 0.20 (0.09-0.33) | |
| Chronic GVHD | |||
| 1 y, total | 0.22 (0.11-0.35) | 0.09 (0.04-0.17) | .03 |
| 1 y, BM only | 0.08 (0.00-0.33) | 0.10 (0.03-0.21) | |
| 1 y, PB only | 0.26 (0.13-0.42) | 0.08 (0.02-0.19) | |
| Variable . | ATG group (95% CI) . | PTCy group (95% CI) . | P . |
|---|---|---|---|
| GRFS | |||
| 1 y, total | 0.16 (0.08-0.31) | 0.54 (0.44-0.66) | <.001 |
| 1 y, BM only | 0.08 (0.01-0.54) | 0.61 (0.48-0.78) | |
| 1 y, PB only | 0.19 (0.09-0.38) | 0.47 (0.34-0.66) | |
| OS | <.001 | ||
| 1 y | 0.45 (0.32-0.62) | 0.75 (0.66-0.85) | |
| 2 y | 0.29 (0.18-0.46) | 0.66 (0.56-0.78) | |
| Event-free survival | <.001 | ||
| 1 y | 0.38 (0.26-0.55) | 0.69 (0.59-0.80) | |
| 2 y | 0.27 (0.17-0.44) | 0.63 (0.53-0.75) | |
| Relapse | .3 | ||
| 1 y | 0.24 (0.13-0.38) | 0.16 (0.09-0.25) | |
| 2 y | 0.26 (0.15-0.4) | 0.19 (0.11-0.29) | |
| NRM | <.001 | ||
| 1 y | 0.38 (0.23-0.52) | 0.16 (0.09-0.25) | |
| 2 y | 0.47 (0.31-0.60) | 0.19 (0.11-0.28) | |
| Acute GVHD (grades 3-4) | |||
| 180 d, total | 0.31 (0.18-0.45) | 0.15 (0.08-0.23) | .03 |
| 180 d, BM only | 0.25 (0.05-0.52) | 0.10 (0.03-0.21) | |
| 180 d, PB only | 0.33 (0.17-0.49) | 0.20 (0.09-0.33) | |
| Chronic GVHD | |||
| 1 y, total | 0.22 (0.11-0.35) | 0.09 (0.04-0.17) | .03 |
| 1 y, BM only | 0.08 (0.00-0.33) | 0.10 (0.03-0.21) | |
| 1 y, PB only | 0.26 (0.13-0.42) | 0.08 (0.02-0.19) | |