Patient characteristics
Variables . | Patients . | ||
---|---|---|---|
No. (n = 25) . | % . | ||
Age at infusion | Median (range) | 59 (20–69) | |
Sex | Male | 14 | 56.0 |
Female | 11 | 44.0 | |
Disease | DLBCL | 25 | 100 |
Disease status at infusion | PR | 4 | 16.0 |
SD | 16 | 64.0 | |
PD | 5 | 20.0 | |
Pre–CAR-T regimens, numbers | Median (range) | 4 (3-12) | |
History of auto-PBSCT | Yes | 9 | 36.0 |
No | 16 | 64.0 | |
Bridging chemotherapy before CAR-T infusion | Yes | 2 (R-CHASE) | 8.0 |
No | 23 | 92.0 | |
Duration | |||
From Dx to Aph, d | Median (range) | 447 (128-3331) | |
From Aph to infusion, d | Median (range) | 64 (47-83) | |
From Dx to infusion, d | Median (range) | 515 (199-3413) |
Variables . | Patients . | ||
---|---|---|---|
No. (n = 25) . | % . | ||
Age at infusion | Median (range) | 59 (20–69) | |
Sex | Male | 14 | 56.0 |
Female | 11 | 44.0 | |
Disease | DLBCL | 25 | 100 |
Disease status at infusion | PR | 4 | 16.0 |
SD | 16 | 64.0 | |
PD | 5 | 20.0 | |
Pre–CAR-T regimens, numbers | Median (range) | 4 (3-12) | |
History of auto-PBSCT | Yes | 9 | 36.0 |
No | 16 | 64.0 | |
Bridging chemotherapy before CAR-T infusion | Yes | 2 (R-CHASE) | 8.0 |
No | 23 | 92.0 | |
Duration | |||
From Dx to Aph, d | Median (range) | 447 (128-3331) | |
From Aph to infusion, d | Median (range) | 64 (47-83) | |
From Dx to infusion, d | Median (range) | 515 (199-3413) |
Aph, apheresis; Dx, diagnosis; PD, progressive disease; PR, partial remission; R-CHASE, rituximab, cyclophosphamide, cytosine arabinoside, etoposide, and dexamethasone; SD, stable disease.