Characteristics associated with differences in cognitive quality of life for allogeneic and autologous HCT survivors, assessed by the Neuro-QoL, version 2.0
| Characteristic . | Allogeneic HCT survivors . | Autologous HCT survivors . | ||||
|---|---|---|---|---|---|---|
| N . | T-score, mean (95% CI) . | % Impaired* . | N . | T-score, mean (95% CI) . | % Impaired* . | |
| Total | 1219 | 50.0 (49.5-50.5)† | 13.9† | 641 | 49.2 (48.5-49.9)† | 17.2† |
| Sex | ||||||
| Female | 583 | 49.3 (48.6-50.0) | 13.9 | 304 | 48.2 (47.2-49.2) | 18.1 |
| Male | 636 | 50.6 (49.9-51.3)† | 13.8 | 337 | 50.2 (49.2-51.1)† | 16.3 |
| Time since initial transplant, y | ||||||
| <5 | 187 | 49.7 (48.3-51.0) | 16.6 | 191 | 50.6 (49.2-51.9) | 14.1 |
| 5-10 | 253 | 48.9 (47.9-50.0) | 14.2 | 186 | 48.2 (46.8-49.6) | 24.2 |
| 10-15 | 168 | 50.0 (48.7-51.3) | 11.9 | 101 | 49.0 (47.4-50.6) | 10.9 |
| 15-20 | 189 | 49.8 (48.6-51.0) | 13.2 | 71 | 49.8 (47.6-52.0) | 15.5 |
| 20-25 | 170 | 51.6 (50.1-53.0) | 11.8 | 54 | 47.8 (45.7-50.0) | 18.5 |
| 25+ | 252 | 50.3 (49.2-51.5) | 14.7 | 38 | 49.1 (46.1-52.1) | 15.8 |
| Current age (by decade) | ||||||
| <50 y | 170 | 48.4 (47.0-49.8) | 18.8 | 51 | 46.6 (43.7-49.5) | 29.4 |
| 50-59 y | 298 | 49.5 (48.4-50.5) | 14.4 | 110 | 49.7 (47.8-51.6) | 17.3 |
| 60-69 y | 479 | 50.6 (49.8-51.4) | 14.8 | 257 | 48.6 (47.4-49.7) | 19.8 |
| ≥70 y | 272 | 50.5 (49.5-51.5) | 8.5 | 223 | 50.4 (49.3-51.4) | 11.2 |
| Hearing issues | ||||||
| No | 877 | 50.7 (50.1-51.3) | 11.6 | 411 | 50.5 (49.6-51.3) | 13.4 |
| Yes | 332 | 48.2 (47.2-49.2)† | 19.9† | 229 | 47.0 (45.8-48.2)† | 24.0† |
| Stroke/seizures | ||||||
| No | 1074 | 50.3 (49.8-50.9) | 13.2 | 572 | 49.5 (48.7-50.2) | 16.8 |
| Yes | 122 | 47.4 (45.7-49.0)† | 19.7 | 55 | 47.0 (44.6-49.5) | 23.6 |
| Sleep disturbance | ||||||
| No (T-score <60) | 1112 | 50.6 (50.1-51.1) | 11.4 | 593 | 49.7 (49.0-50.5) | 15.7 |
| Yes (T-score ≥60) | 104 | 43.6 (41.9-45.3)† | 38.5† | 47 | 43.0 (40.6-45.4)† | 36.2† |
| Characteristic . | Allogeneic HCT survivors . | Autologous HCT survivors . | ||||
|---|---|---|---|---|---|---|
| N . | T-score, mean (95% CI) . | % Impaired* . | N . | T-score, mean (95% CI) . | % Impaired* . | |
| Total | 1219 | 50.0 (49.5-50.5)† | 13.9† | 641 | 49.2 (48.5-49.9)† | 17.2† |
| Sex | ||||||
| Female | 583 | 49.3 (48.6-50.0) | 13.9 | 304 | 48.2 (47.2-49.2) | 18.1 |
| Male | 636 | 50.6 (49.9-51.3)† | 13.8 | 337 | 50.2 (49.2-51.1)† | 16.3 |
| Time since initial transplant, y | ||||||
| <5 | 187 | 49.7 (48.3-51.0) | 16.6 | 191 | 50.6 (49.2-51.9) | 14.1 |
| 5-10 | 253 | 48.9 (47.9-50.0) | 14.2 | 186 | 48.2 (46.8-49.6) | 24.2 |
| 10-15 | 168 | 50.0 (48.7-51.3) | 11.9 | 101 | 49.0 (47.4-50.6) | 10.9 |
| 15-20 | 189 | 49.8 (48.6-51.0) | 13.2 | 71 | 49.8 (47.6-52.0) | 15.5 |
| 20-25 | 170 | 51.6 (50.1-53.0) | 11.8 | 54 | 47.8 (45.7-50.0) | 18.5 |
| 25+ | 252 | 50.3 (49.2-51.5) | 14.7 | 38 | 49.1 (46.1-52.1) | 15.8 |
| Current age (by decade) | ||||||
| <50 y | 170 | 48.4 (47.0-49.8) | 18.8 | 51 | 46.6 (43.7-49.5) | 29.4 |
| 50-59 y | 298 | 49.5 (48.4-50.5) | 14.4 | 110 | 49.7 (47.8-51.6) | 17.3 |
| 60-69 y | 479 | 50.6 (49.8-51.4) | 14.8 | 257 | 48.6 (47.4-49.7) | 19.8 |
| ≥70 y | 272 | 50.5 (49.5-51.5) | 8.5 | 223 | 50.4 (49.3-51.4) | 11.2 |
| Hearing issues | ||||||
| No | 877 | 50.7 (50.1-51.3) | 11.6 | 411 | 50.5 (49.6-51.3) | 13.4 |
| Yes | 332 | 48.2 (47.2-49.2)† | 19.9† | 229 | 47.0 (45.8-48.2)† | 24.0† |
| Stroke/seizures | ||||||
| No | 1074 | 50.3 (49.8-50.9) | 13.2 | 572 | 49.5 (48.7-50.2) | 16.8 |
| Yes | 122 | 47.4 (45.7-49.0)† | 19.7 | 55 | 47.0 (44.6-49.5) | 23.6 |
| Sleep disturbance | ||||||
| No (T-score <60) | 1112 | 50.6 (50.1-51.1) | 11.4 | 593 | 49.7 (49.0-50.5) | 15.7 |
| Yes (T-score ≥60) | 104 | 43.6 (41.9-45.3)† | 38.5† | 47 | 43.0 (40.6-45.4)† | 36.2† |