Table 2. Correlations of frequency of... | American Society of Hematology

Table 2.

Correlations of frequency of different activated CD8⁺ T-cell subpopulations with laboratory parameters of MAS activity/severity and circulating levels of the MAS/HLH biomarkers CXCL9 and IL-18

CD8⁺ T cell subset	Spearman correlation (r), P-value (P)	Ferritin	Hemoglobin	Neutrophils	Platelets	AST	LDH	Triglycerides	Fibrinogen	CXCL9	IL-18
CD38^high/HLA-DR⁺CD8⁺	r	0.60	−0.68	0.055	0.008	0.43	0.74	0.49	−0.52	0.41	0.68
CD38^high/HLA-DR⁺CD8⁺	P	.02	.009	.85	.97	.13	.003	.07	.056	.14	.009
CD4^dimCD8⁺	r	0.55	−0.50	−0.14	−0.23	0.65	0.8	0.73	−0.73	0.59	0.58
CD4^dimCD8⁺	P	.046	.07	.62	.41	.013	.001	.004	.004	.02	.03

CD8⁺ T cell subset	Spearman correlation (r), P-value (P)	Ferritin	Hemoglobin	Neutrophils	Platelets	AST	LDH	Triglycerides	Fibrinogen	CXCL9	IL-18
CD38^high/HLA-DR⁺CD8⁺	r	0.60	−0.68	0.055	0.008	0.43	0.74	0.49	−0.52	0.41	0.68
CD38^high/HLA-DR⁺CD8⁺	P	.02	.009	.85	.97	.13	.003	.07	.056	.14	.009
CD4^dimCD8⁺	r	0.55	−0.50	−0.14	−0.23	0.65	0.8	0.73	−0.73	0.59	0.58
CD4^dimCD8⁺	P	.046	.07	.62	.41	.013	.001	.004	.004	.02	.03

Statistically significant correlations (P < .05) and the respective Spearman correlation coefficient are italic.

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