Baseline patient characteristics
| Characteristic . | Azacitidine (n = 171) . | Decitabine (n = 167) . | P . |
|---|---|---|---|
| Age, years | .95 | ||
| Median | 76 | 76 | |
| Range | 59-94 | 60-87 | |
| Sex | .38 | ||
| Male | 61 | 56 | |
| Female | 39 | 44 | |
| ECOG PS | .23 | ||
| 0-1 | 53 | 46 | |
| 2-3 | 47 | 54 | |
| Secondary AML | 38 | 37 | .82 |
| Poor-risk cytogenetics | 38 | 34 | .43 |
| Total WBCs ≥20 000/μL | 15 | 13 | .64 |
| BM blasts >30% | 64 | 71 | .16 |
| TP53 mutation | 11.7 | 11.4 | >.99 |
| Geographic location* | .049 | ||
| North America (n = 75) | 45 | 55 | |
| Europe (n = 213) | 55 | 45 | |
| Rest of the world (n = 50) | 38 | 62 |
| Characteristic . | Azacitidine (n = 171) . | Decitabine (n = 167) . | P . |
|---|---|---|---|
| Age, years | .95 | ||
| Median | 76 | 76 | |
| Range | 59-94 | 60-87 | |
| Sex | .38 | ||
| Male | 61 | 56 | |
| Female | 39 | 44 | |
| ECOG PS | .23 | ||
| 0-1 | 53 | 46 | |
| 2-3 | 47 | 54 | |
| Secondary AML | 38 | 37 | .82 |
| Poor-risk cytogenetics | 38 | 34 | .43 |
| Total WBCs ≥20 000/μL | 15 | 13 | .64 |
| BM blasts >30% | 64 | 71 | .16 |
| TP53 mutation | 11.7 | 11.4 | >.99 |
| Geographic location* | .049 | ||
| North America (n = 75) | 45 | 55 | |
| Europe (n = 213) | 55 | 45 | |
| Rest of the world (n = 50) | 38 | 62 |
Values are given as percentages, unless otherwise indicated.
WBC, white blood cell.
Percentages under Geographic Location are based on the corresponding total n in each geographic location.