Table 1.

Baseline patient characteristics

CharacteristicAzacitidine
(n = 171)
Decitabine
(n = 167)
P
Age, years   .95 
 Median 76 76  
 Range 59-94 60-87  
Sex   .38 
 Male 61 56  
 Female 39 44  
ECOG PS   .23 
 0-1 53 46  
 2-3 47 54  
Secondary AML 38 37 .82 
Poor-risk cytogenetics 38 34 .43 
Total WBCs ≥20 000/μL 15 13 .64 
BM blasts >30% 64 71 .16 
TP53 mutation 11.7 11.4 >.99 
Geographic location*   .049 
 North America (n = 75) 45 55  
 Europe (n = 213) 55 45  
 Rest of the world (n = 50) 38 62  
CharacteristicAzacitidine
(n = 171)
Decitabine
(n = 167)
P
Age, years   .95 
 Median 76 76  
 Range 59-94 60-87  
Sex   .38 
 Male 61 56  
 Female 39 44  
ECOG PS   .23 
 0-1 53 46  
 2-3 47 54  
Secondary AML 38 37 .82 
Poor-risk cytogenetics 38 34 .43 
Total WBCs ≥20 000/μL 15 13 .64 
BM blasts >30% 64 71 .16 
TP53 mutation 11.7 11.4 >.99 
Geographic location*   .049 
 North America (n = 75) 45 55  
 Europe (n = 213) 55 45  
 Rest of the world (n = 50) 38 62  

Values are given as percentages, unless otherwise indicated.

WBC, white blood cell.

*

Percentages under Geographic Location are based on the corresponding total n in each geographic location.

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