Multivariable OS analyses of gene mutations
| Variable . | Multivariable . | ||
|---|---|---|---|
| HR . | 95% CI . | P . | |
| ASXL1 and CBL | |||
| ASXL1 | 2.26 | 1.04-4.93 | .04 |
| CBL | 4.16 | 1.65-10.54 | .003 |
| ASXL1 and RAS-pathway | |||
| ASXL1 | 2.47 | 1.13-5.37 | .023 |
| RAS-pathway mutations | 3.91 | 1.74-8.77 | .001 |
| Variable . | Multivariable . | ||
|---|---|---|---|
| HR . | 95% CI . | P . | |
| ASXL1 and CBL | |||
| ASXL1 | 2.26 | 1.04-4.93 | .04 |
| CBL | 4.16 | 1.65-10.54 | .003 |
| ASXL1 and RAS-pathway | |||
| ASXL1 | 2.47 | 1.13-5.37 | .023 |
| RAS-pathway mutations | 3.91 | 1.74-8.77 | .001 |
Multivariable analyses assessed on genes mutated in at least 10 patients. RAS-pathway mutations are mutations in CBL, NRAS, and/or KRAS gene.