Univariable OS analyses of gene mutations
| Variable . | HR . | 95% CI . | P . |
|---|---|---|---|
| ASXL1 | 2.55 | 1.18-5.51 | .018 |
| CBL | 4.67 | 1.87-11.69 | .001 |
| RUNX1 | 2.71 | 0.91-8.08 | .075 |
| NRAS | 3.5 | 1.17-10.49 | .025 |
| RAS-pathway mutations | 3.93 | 1.78-8.67 | .001 |
| TP53 | 10.72 | 3.79-30.29 | <.001 |
| SH2B3 | 4.34 | 1.47-12.81 | .008 |
| Variable . | HR . | 95% CI . | P . |
|---|---|---|---|
| ASXL1 | 2.55 | 1.18-5.51 | .018 |
| CBL | 4.67 | 1.87-11.69 | .001 |
| RUNX1 | 2.71 | 0.91-8.08 | .075 |
| NRAS | 3.5 | 1.17-10.49 | .025 |
| RAS-pathway mutations | 3.93 | 1.78-8.67 | .001 |
| TP53 | 10.72 | 3.79-30.29 | <.001 |
| SH2B3 | 4.34 | 1.47-12.81 | .008 |
RAS-pathway mutations are mutations in CBL, NRAS, and/or KRAS gene.