Interpretation of certainty in the evidence about effects
| High certainty ⨁⨁⨁⨁ | There is almost no uncertainty regarding where the true effect of the intervention lies |
| Moderate certainty ⨁⨁⨁◯ | There is little uncertainty regarding where the true effect of the intervention lies |
| Low certainty ⨁⨁◯◯ | There is uncertainty regarding where the true effect of the intervention lies |
| Very-low certainty ⨁◯◯◯ | There is considerable uncertainty regarding where the true effect of the intervention lies |
| High certainty ⨁⨁⨁⨁ | There is almost no uncertainty regarding where the true effect of the intervention lies |
| Moderate certainty ⨁⨁⨁◯ | There is little uncertainty regarding where the true effect of the intervention lies |
| Low certainty ⨁⨁◯◯ | There is uncertainty regarding where the true effect of the intervention lies |
| Very-low certainty ⨁◯◯◯ | There is considerable uncertainty regarding where the true effect of the intervention lies |