Table 1.

Clinical questions adapted

Prevention of VTE in surgical patients 
 VTE prophylaxis vs no prophylaxis for patients undergoing major general surgery 
 VTE prophylaxis vs no prophylaxis for patients undergoing surgery following major trauma 
 VTE prophylaxis vs no prophylaxis for patients undergoing laparoscopic cholecystectomy 
 VTE prophylaxis vs no prophylaxis for patients undergoing transurethral resection of the prostate 
 VTE prophylaxis vs no prophylaxis for patients undergoing radical prostatectomy 
 VTE pharmacological prophylaxis vs no prophylaxis for patients undergoing major neurosurgical procedures 
 Mechanical vs pharmacological prophylaxis 
 Short-term (7 to 10 d) vs extended prophylaxis (30 d) 
 Delayed initiation vs early administration of pharmacological prophylaxis 
 Mechanical compression devices vs compression stockings 
Prevention of VTE in medical patients 
 UFH vs LMWH in critically and acutely ill patients 
 Prophylaxis vs no prophylaxis in acutely ill patients 
 DOACs vs no prophylaxis 
 Short period vs extended prophylaxis 
 Prophylaxis vs no prophylaxis in chronically ill patients 
 Mechanical prophylaxis vs no prophylaxis for patients who cannot receive pharmacological prophylaxis 
 Compression stockings vs mechanical compression devices 
Prevention of vein thromboembolism in long-distance travelers 
 Prophylaxis with LMWH vs no prophylaxis 
 Prophylaxis with compression stockings vs no prophylaxis 
Prevention of VTE in surgical patients 
 VTE prophylaxis vs no prophylaxis for patients undergoing major general surgery 
 VTE prophylaxis vs no prophylaxis for patients undergoing surgery following major trauma 
 VTE prophylaxis vs no prophylaxis for patients undergoing laparoscopic cholecystectomy 
 VTE prophylaxis vs no prophylaxis for patients undergoing transurethral resection of the prostate 
 VTE prophylaxis vs no prophylaxis for patients undergoing radical prostatectomy 
 VTE pharmacological prophylaxis vs no prophylaxis for patients undergoing major neurosurgical procedures 
 Mechanical vs pharmacological prophylaxis 
 Short-term (7 to 10 d) vs extended prophylaxis (30 d) 
 Delayed initiation vs early administration of pharmacological prophylaxis 
 Mechanical compression devices vs compression stockings 
Prevention of VTE in medical patients 
 UFH vs LMWH in critically and acutely ill patients 
 Prophylaxis vs no prophylaxis in acutely ill patients 
 DOACs vs no prophylaxis 
 Short period vs extended prophylaxis 
 Prophylaxis vs no prophylaxis in chronically ill patients 
 Mechanical prophylaxis vs no prophylaxis for patients who cannot receive pharmacological prophylaxis 
 Compression stockings vs mechanical compression devices 
Prevention of vein thromboembolism in long-distance travelers 
 Prophylaxis with LMWH vs no prophylaxis 
 Prophylaxis with compression stockings vs no prophylaxis 
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