Table 4.

Details of events occurred from 3 and 6 months of follow-up

SexAge (y)Type of eventEvent time (d)Event details
69 SVT recurrence 96 Symptomatic portal vein thrombosis in infiltrative hepatocellular carcinoma during treatment with rivaroxaban 20 mg once daily; switched to LMWH 
76 Death (non–SVT related)* 98 Death for clinical deterioration in esophageal cancer progression 
70 CRNMB 102 Profuse epistaxis during treatment with rivaroxaban 20 mg once daily; finding of varices of the nasal septum treated with nasal packing; anticoagulation was temporarily stopped and then restarted on reduced dose of rivaroxaban 
44 CRNMB 117 Menometrorrhagia with mild anemia during treatment with rivaroxaban 20 mg once daily; treated with tranexamic acid; patient was then switched to VKA 
73 Death (non–SVT related) 136 Death for clinical deterioration in pancreatic cancer progression 
55 MB 187 Rectorrhagia in adenocarcinoma of the rectum with intestinal stoma; during treatment with rivaroxaban 20 mg once daily, severe anemia (Hb drop ≥2 g/dL) required hospitalization and red blood cells transfusion; anticoagulation was temporarily stopped; patient was then switched to LMWH 
SexAge (y)Type of eventEvent time (d)Event details
69 SVT recurrence 96 Symptomatic portal vein thrombosis in infiltrative hepatocellular carcinoma during treatment with rivaroxaban 20 mg once daily; switched to LMWH 
76 Death (non–SVT related)* 98 Death for clinical deterioration in esophageal cancer progression 
70 CRNMB 102 Profuse epistaxis during treatment with rivaroxaban 20 mg once daily; finding of varices of the nasal septum treated with nasal packing; anticoagulation was temporarily stopped and then restarted on reduced dose of rivaroxaban 
44 CRNMB 117 Menometrorrhagia with mild anemia during treatment with rivaroxaban 20 mg once daily; treated with tranexamic acid; patient was then switched to VKA 
73 Death (non–SVT related) 136 Death for clinical deterioration in pancreatic cancer progression 
55 MB 187 Rectorrhagia in adenocarcinoma of the rectum with intestinal stoma; during treatment with rivaroxaban 20 mg once daily, severe anemia (Hb drop ≥2 g/dL) required hospitalization and red blood cells transfusion; anticoagulation was temporarily stopped; patient was then switched to LMWH 
*

Same patient with previously 1 MB.

Same patient with previously 2 CRNMB.

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