Laboratory data
| Variable . | Reference range . | At time of referral . | 15 mo after initial presentation . |
|---|---|---|---|
| Hb, g/dL | 11.6-15.5 | 7.8 | |
| RBC, ×1012/L | 4.0-5.2 | 3.95 | |
| Hematocrit, % | 34.6-45.3 | 20.9 | |
| MCV, fL | 80.0-95.5 | 91.7 (103*) | |
| MCH, pg | 26.1-32.6 | 34.2 (36*) | |
| MCHC, g/dL | 31.9-35.5 | 37.3 (35*) | |
| Reticulocytes, % | 0.54-2.02 | 0.57 | |
| Red cell distribution width, % | <15 | 12.9 | |
| RPI | >2† | 0.1 | |
| Reticulocytes, ×109/L | 19.8-80.7 | 13 | |
| Platelets, ×109/L | 176-391 | 527 | |
| White blood cells, ×109/L | 4.0-10.4 | 3.29 | |
| Differential count, % | |||
| Neutrophils | 40-70 | 72 | |
| Lymphocytes | 20-40 | 22 | |
| Monocytes | 3-7 | 5 | |
| Eosinophils | 2-4 | 0 | |
| Basophils | 0-1 | 0 | |
| Iron, µg/dL | 37-145 | 63 | |
| Transferrin, mg/dL | 200-360 | 169 | |
| Transferrin saturation, % | 16-45 | 26 | |
| Ferritin, ng/mL | 15-150 | 372 | |
| Soluble transferrin receptor, mg/L | 1.9-4.4 | 0.7‡ | |
| Hepcidin, ng/mL | 1.5-41.5 | 34 | |
| Zinc protoporphyrin, µmol/mol haem | <40 | 26.5 | |
| Potassium, mmol/L | 3.5-5.1 | 4.5 | |
| Haptoglobin, mg/dL | 30-200 | 223 | |
| Lactate dehydrogenase, U/L | 135-214 | 173 | |
| Total bilirubin, mg/dL | <0.9 | 1.0 | |
| CRP, mg/L | <5 | 40 | |
| α-1-Globulin, % | 2.9-4.9 | 8.0 | |
| α-2-Globulin, % | 7.1-11.8 | 11.5 | |
| β-Globulin, % | 7.9-13.7 | 11.0 | |
| γ-Globulin, % | 11.1-18.8 | 10.9 | |
| IgA, mg/dL | 70-400 | 150 | |
| IgG, mg/dL | 700-1600 | 654 | |
| IgM, mg/dL | 40-230 | 228 | |
| Erythropoietin, mU/mL | 4.3-29 | 508 | |
| Vitamin B12, pg/mL | 197-771 | 519 | |
| Folate, ng/mL | 4.6-34.8 | 14.1 | |
| IL-2 receptor, U/mL | 158-623 | 179 | |
| IL-1 β, pg/mL | <5 | <5 | |
| IL-6, pg/mL | <7 | <1.5 | |
| IL-10, pg/mL | <9.1 | <1.0 | |
| TNF-α, pg/mL | <8.1 | 12.0 | |
| Glutathione | |||
| Total, µmol/L | 1669 | ||
| Reduced, µmol/L | 500-1500 | 1314 | |
| Oxidized, µmol/L | 25-150 | 178 | |
| Malondialdehyde, µmol/L | 0.36-1.2 | 1.5 |
| Variable . | Reference range . | At time of referral . | 15 mo after initial presentation . |
|---|---|---|---|
| Hb, g/dL | 11.6-15.5 | 7.8 | |
| RBC, ×1012/L | 4.0-5.2 | 3.95 | |
| Hematocrit, % | 34.6-45.3 | 20.9 | |
| MCV, fL | 80.0-95.5 | 91.7 (103*) | |
| MCH, pg | 26.1-32.6 | 34.2 (36*) | |
| MCHC, g/dL | 31.9-35.5 | 37.3 (35*) | |
| Reticulocytes, % | 0.54-2.02 | 0.57 | |
| Red cell distribution width, % | <15 | 12.9 | |
| RPI | >2† | 0.1 | |
| Reticulocytes, ×109/L | 19.8-80.7 | 13 | |
| Platelets, ×109/L | 176-391 | 527 | |
| White blood cells, ×109/L | 4.0-10.4 | 3.29 | |
| Differential count, % | |||
| Neutrophils | 40-70 | 72 | |
| Lymphocytes | 20-40 | 22 | |
| Monocytes | 3-7 | 5 | |
| Eosinophils | 2-4 | 0 | |
| Basophils | 0-1 | 0 | |
| Iron, µg/dL | 37-145 | 63 | |
| Transferrin, mg/dL | 200-360 | 169 | |
| Transferrin saturation, % | 16-45 | 26 | |
| Ferritin, ng/mL | 15-150 | 372 | |
| Soluble transferrin receptor, mg/L | 1.9-4.4 | 0.7‡ | |
| Hepcidin, ng/mL | 1.5-41.5 | 34 | |
| Zinc protoporphyrin, µmol/mol haem | <40 | 26.5 | |
| Potassium, mmol/L | 3.5-5.1 | 4.5 | |
| Haptoglobin, mg/dL | 30-200 | 223 | |
| Lactate dehydrogenase, U/L | 135-214 | 173 | |
| Total bilirubin, mg/dL | <0.9 | 1.0 | |
| CRP, mg/L | <5 | 40 | |
| α-1-Globulin, % | 2.9-4.9 | 8.0 | |
| α-2-Globulin, % | 7.1-11.8 | 11.5 | |
| β-Globulin, % | 7.9-13.7 | 11.0 | |
| γ-Globulin, % | 11.1-18.8 | 10.9 | |
| IgA, mg/dL | 70-400 | 150 | |
| IgG, mg/dL | 700-1600 | 654 | |
| IgM, mg/dL | 40-230 | 228 | |
| Erythropoietin, mU/mL | 4.3-29 | 508 | |
| Vitamin B12, pg/mL | 197-771 | 519 | |
| Folate, ng/mL | 4.6-34.8 | 14.1 | |
| IL-2 receptor, U/mL | 158-623 | 179 | |
| IL-1 β, pg/mL | <5 | <5 | |
| IL-6, pg/mL | <7 | <1.5 | |
| IL-10, pg/mL | <9.1 | <1.0 | |
| TNF-α, pg/mL | <8.1 | 12.0 | |
| Glutathione | |||
| Total, µmol/L | 1669 | ||
| Reduced, µmol/L | 500-1500 | 1314 | |
| Oxidized, µmol/L | 25-150 | 178 | |
| Malondialdehyde, µmol/L | 0.36-1.2 | 1.5 |
IL, interleukin; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; RPI, reticulocyte production index; TNF, tumor necrosis factor.
Before red blood cell transfusions and referral to Freiburg University Hospital.
Anemia with adequate regeneration.
Determined 3 mo after initial consultation.