Table 1.

HLA-DQ molecules in the study population

Patient genotype
Number of unique molecules in 5164 HLA-matched patients*  
 Total number of G1  
  None G2G2 (n = 900) 
  One G1G1 (n = 292) 
 G1G2 (n = 2573) 
  Two G1G1 (n = 520) 
  Four G1G1 (n = 879) 
 Total number of G2  
  None G1G1 (n = 1691) 
  One G2G2 (n = 240) 
 G1G2 (n = 2573) 
  Two G2G2 (n = 115) 
  Four G2G2 (n = 545) 
Number of mismatched molecules in 520 HLA-DQ–mismatched patients  
 One (n = 324) G1: G1G1 (n = 32) 
 G1G2 (n = 148) 
 G2: G1G2 (n = 123) 
 G2G2 (n = 21) 
 Two (n = 155) G1: G1G1 (n = 128) 
 G2: G2G2 (n = 27) 
 Three (n = 41) G1: G1G1 (n = 22) 
 G2: G2G2 (n = 19) 
Patient genotype
Number of unique molecules in 5164 HLA-matched patients*  
 Total number of G1  
  None G2G2 (n = 900) 
  One G1G1 (n = 292) 
 G1G2 (n = 2573) 
  Two G1G1 (n = 520) 
  Four G1G1 (n = 879) 
 Total number of G2  
  None G1G1 (n = 1691) 
  One G2G2 (n = 240) 
 G1G2 (n = 2573) 
  Two G2G2 (n = 115) 
  Four G2G2 (n = 545) 
Number of mismatched molecules in 520 HLA-DQ–mismatched patients  
 One (n = 324) G1: G1G1 (n = 32) 
 G1G2 (n = 148) 
 G2: G1G2 (n = 123) 
 G2G2 (n = 21) 
 Two (n = 155) G1: G1G1 (n = 128) 
 G2: G2G2 (n = 27) 
 Three (n = 41) G1: G1G1 (n = 22) 
 G2: G2G2 (n = 19) 
*

The total number of unique molecules in HLA-matched patients depends on the genotype, potential for trans-dimerization, and homozygosity of alleles.

The total number of mismatched molecules depends on the genotype, potential for trans-dimerization, and homozygosity of alleles. In HLA-DQ–mismatched transplants, the mismatched molecule is underlined.

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