HLA-DQ molecules in the study population
. | Patient genotype . |
---|---|
Number of unique molecules in 5164 HLA-matched patients* | |
Total number of G1 | |
None | G2G2 (n = 900) |
One | G1G1 (n = 292) |
G1G2 (n = 2573) | |
Two | G1G1 (n = 520) |
Four | G1G1 (n = 879) |
Total number of G2 | |
None | G1G1 (n = 1691) |
One | G2G2 (n = 240) |
G1G2 (n = 2573) | |
Two | G2G2 (n = 115) |
Four | G2G2 (n = 545) |
Number of mismatched molecules in 520 HLA-DQ–mismatched patients† | |
One (n = 324) | G1: G1G1 (n = 32) |
G1G2 (n = 148) | |
G2: G1G2 (n = 123) | |
G2G2 (n = 21) | |
Two (n = 155) | G1: G1G1 (n = 128) |
G2: G2G2 (n = 27) | |
Three (n = 41) | G1: G1G1 (n = 22) |
G2: G2G2 (n = 19) |
. | Patient genotype . |
---|---|
Number of unique molecules in 5164 HLA-matched patients* | |
Total number of G1 | |
None | G2G2 (n = 900) |
One | G1G1 (n = 292) |
G1G2 (n = 2573) | |
Two | G1G1 (n = 520) |
Four | G1G1 (n = 879) |
Total number of G2 | |
None | G1G1 (n = 1691) |
One | G2G2 (n = 240) |
G1G2 (n = 2573) | |
Two | G2G2 (n = 115) |
Four | G2G2 (n = 545) |
Number of mismatched molecules in 520 HLA-DQ–mismatched patients† | |
One (n = 324) | G1: G1G1 (n = 32) |
G1G2 (n = 148) | |
G2: G1G2 (n = 123) | |
G2G2 (n = 21) | |
Two (n = 155) | G1: G1G1 (n = 128) |
G2: G2G2 (n = 27) | |
Three (n = 41) | G1: G1G1 (n = 22) |
G2: G2G2 (n = 19) |
The total number of unique molecules in HLA-matched patients depends on the genotype, potential for trans-dimerization, and homozygosity of alleles.
The total number of mismatched molecules depends on the genotype, potential for trans-dimerization, and homozygosity of alleles. In HLA-DQ–mismatched transplants, the mismatched molecule is underlined.