Characteristics and clinical data of patients with COVID-19
| Patient no. . | Diagnosis/ phase . | Rare complement gene variants . | Variant classification . | ExAC global frequency . | Gender . | Platelets (140-400 000/μL) . | Hb (14-18 g/dL) . | D-Dimer (0-500 ng/mL) . | s-Creatinine (0.55-1.25 mg/dL) . | PaO2/FiO2 ratio (400-500 mm Hg) . | Plasma sC5b9 (127-400 ng/mL) . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 012 | COVID+ CPAP | No | — | — | M | 175 000 | 11.9 | 6433 | 0.71 | 221 | 501 |
| 013 | COVID+ CPAP | C3 – L476I | US | NA | M | 403 000 | 12.2 | 572 | 0.78 | 265 | 638 |
| 014 | COVID+ CPAP | No | — | — | F | 168 000 | 13.6 | 853 | 0.69 | 202 | 669 |
| 015 | COVID+ CPAP | No | — | — | F | 127 000 | 10.8 | 2951 | 1.46 | 112 | 531 |
| 016 | COVID+ CPAP | No | — | — | M | 255 000 | 15.7 | 1042 | 1.1 | 148 | 1009 |
| 017 | COVID+ CPAP | No | — | — | M | 447 000 | 12.9 | 955 | 0.69 | 103 | 1093 |
| Patient no. . | Diagnosis/ phase . | Rare complement gene variants . | Variant classification . | ExAC global frequency . | Gender . | Platelets (140-400 000/μL) . | Hb (14-18 g/dL) . | D-Dimer (0-500 ng/mL) . | s-Creatinine (0.55-1.25 mg/dL) . | PaO2/FiO2 ratio (400-500 mm Hg) . | Plasma sC5b9 (127-400 ng/mL) . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 012 | COVID+ CPAP | No | — | — | M | 175 000 | 11.9 | 6433 | 0.71 | 221 | 501 |
| 013 | COVID+ CPAP | C3 – L476I | US | NA | M | 403 000 | 12.2 | 572 | 0.78 | 265 | 638 |
| 014 | COVID+ CPAP | No | — | — | F | 168 000 | 13.6 | 853 | 0.69 | 202 | 669 |
| 015 | COVID+ CPAP | No | — | — | F | 127 000 | 10.8 | 2951 | 1.46 | 112 | 531 |
| 016 | COVID+ CPAP | No | — | — | M | 255 000 | 15.7 | 1042 | 1.1 | 148 | 1009 |
| 017 | COVID+ CPAP | No | — | — | M | 447 000 | 12.9 | 955 | 0.69 | 103 | 1093 |
CPAP, continuous-positive-airway-pressure; F, female; Hb, hemoglobin; M, male; NA, not available; US, unknown significance.