Table 3. Mean (range) T-score difference... | American Society of Hematology

Table 3.

Mean (range) T-score difference from baseline to EOS and baseline to EOT at lumbar spine, total hip, and femoral neck, respectively (efficacy group; 47 patients)

	ΔT_EOS (ALN)	ΔT_EOS (placebo)	Difference	P
EOS (12 mo)
Lumbar spine*	0.15 (−0.70 to 0.90)	−0.12 (−0.80 to 0.80)	0.28 (0.04−0.51)	.023
Total hip†	−0.05 (−0.70 to 0.30)	−0.10 (−0.40 to 0.30)	0.05	.175
Femoral neck*	−0.07 (−0.60 to 0.40)	−0.10 (−0.50 to 0.30)	0.03 (−0.11 to 0.18)	.624
EOT (4 to 6 mo)
Lumbar spine*	0.01 (−0.60 to 0.70)	−0.00 (−0.60 to 1.00)	0.01 (−0.19 to 0.22)	.896
Total hip‡	−0.05 (−0.70 to 0.50)	−0.05 (−0.30 to 0.20)	0.00 (−0.12 to 0.12)	1.000
Femoral neck†	−0.11 (−0.40 to 0.40)	−0.02 (−0.40 to 0.30)	−0.10	.175

	ΔT_EOS (ALN)	ΔT_EOS (placebo)	Difference	P
EOS (12 mo)
Lumbar spine*	0.15 (−0.70 to 0.90)	−0.12 (−0.80 to 0.80)	0.28 (0.04−0.51)	.023
Total hip†	−0.05 (−0.70 to 0.30)	−0.10 (−0.40 to 0.30)	0.05	.175
Femoral neck*	−0.07 (−0.60 to 0.40)	−0.10 (−0.50 to 0.30)	0.03 (−0.11 to 0.18)	.624
EOT (4 to 6 mo)
Lumbar spine*	0.01 (−0.60 to 0.70)	−0.00 (−0.60 to 1.00)	0.01 (−0.19 to 0.22)	.896
Total hip‡	−0.05 (−0.70 to 0.50)	−0.05 (−0.30 to 0.20)	0.00 (−0.12 to 0.12)	1.000
Femoral neck†	−0.11 (−0.40 to 0.40)	−0.02 (−0.40 to 0.30)	−0.10	.175

Student t test with equal variance.

†

Wilcoxon rank-sum test (no confidence intervals are provided from this test).

‡

Student t test with unequal variance.

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