Summary of the frequency of PNH clones detection in patients with IBMFS according to previous studies
| Study . | Disease (n) . | Patients with IBMFS who have a PNH clone . | Cutoff value . | Year . |
|---|---|---|---|---|
| Keller et al6 | SDS (3), SDS likely (16), SDS possible (7) | 0/26 | Red cells >1.0% | |
| Neutrophils >1.0% | ||||
| DeZern et al4 | DC (9), FA (4), DBA (2), SDS (3), c-MPL (2) | 0/20 | 0.1% | 2000-2008 |
| 0.01% | 2009-2014 | |||
| Shah et al1 | DC (3), FA (2), DBA (1), Others (3) | 0/9 | Granulocytes >1.0% | 2010-2018 |
| Erythrocytes >1.0% | 2010-2018 | |||
| Granulocytes >0.05% | 2018-2020 | |||
| Monocytes >0.3% | 2018-2020 | |||
| Erythrocytes >0.01% | 2018-2020 | |||
| Our data | DC (8), FA (9), DBA (3), SDS (1) | 9/21 | Granulocytes >0.020% | |
| Erythrocytes >0.037% |
| Study . | Disease (n) . | Patients with IBMFS who have a PNH clone . | Cutoff value . | Year . |
|---|---|---|---|---|
| Keller et al6 | SDS (3), SDS likely (16), SDS possible (7) | 0/26 | Red cells >1.0% | |
| Neutrophils >1.0% | ||||
| DeZern et al4 | DC (9), FA (4), DBA (2), SDS (3), c-MPL (2) | 0/20 | 0.1% | 2000-2008 |
| 0.01% | 2009-2014 | |||
| Shah et al1 | DC (3), FA (2), DBA (1), Others (3) | 0/9 | Granulocytes >1.0% | 2010-2018 |
| Erythrocytes >1.0% | 2010-2018 | |||
| Granulocytes >0.05% | 2018-2020 | |||
| Monocytes >0.3% | 2018-2020 | |||
| Erythrocytes >0.01% | 2018-2020 | |||
| Our data | DC (8), FA (9), DBA (3), SDS (1) | 9/21 | Granulocytes >0.020% | |
| Erythrocytes >0.037% |
DBA, Diamond–Blackfan anemia.