Table 4. AEs (safety population [ N =... | American Society of Hematology

Table 4.

AEs (safety population [N = 100])

AE	Any grade	Grade ≥3
All AEs	100 (100)	74 (74)
Asthenia	51 (51)	2 (2)
Neutropenia*	48 (48)	47 (47)
Constipation	42 (42)	0 (0)
Cough	36 (36)	2 (2)
Diarrhea	35 (35)	2 (2)
Infusion-related reaction	28 (28)	3 (3)
Bronchitis	27 (27)	0 (0)
Decreased weight	26 (26)	1 (1)
Arthralgia	25 (25)	0 (0)
Rash	25 (25)	2 (2)
Rhinitis	21 (21)	0 (0)
Nausea	18 (18)	1 (1)
Nasopharyngitis	17 (17)	0 (0)
Back pain	15 (15)	0 (0)
Pruritus	15 (15)	1 (1)
Urinary tract infection	15 (15)	0 (0)
Peripheral edema	13 (13)	1 (1)
Muscle spasms	12 (12)	1 (1)
Upper abdominal pain	11 (11)	0 (0)
Erythema	11 (11)	0 (0)
Peripheral neuropathy†	11 (11)	1 (1)
Sinusitis	11 (11)	0 (0)

AE	Any grade	Grade ≥3
All AEs	100 (100)	74 (74)
Asthenia	51 (51)	2 (2)
Neutropenia*	48 (48)	47 (47)
Constipation	42 (42)	0 (0)
Cough	36 (36)	2 (2)
Diarrhea	35 (35)	2 (2)
Infusion-related reaction	28 (28)	3 (3)
Bronchitis	27 (27)	0 (0)
Decreased weight	26 (26)	1 (1)
Arthralgia	25 (25)	0 (0)
Rash	25 (25)	2 (2)
Rhinitis	21 (21)	0 (0)
Nausea	18 (18)	1 (1)
Nasopharyngitis	17 (17)	0 (0)
Back pain	15 (15)	0 (0)
Pruritus	15 (15)	1 (1)
Urinary tract infection	15 (15)	0 (0)
Peripheral edema	13 (13)	1 (1)
Muscle spasms	12 (12)	1 (1)
Upper abdominal pain	11 (11)	0 (0)
Erythema	11 (11)	0 (0)
Peripheral neuropathy†	11 (11)	1 (1)
Sinusitis	11 (11)	0 (0)

Data are presented as no. (%).

Included combined preferred terms: neutropenia, neutrophil count decreased, neutrophil percentage decreased, and band neutrophil count decreased.

Included combined preferred terms: neuropathy peripheral, peripheral sensory neuropathy, and paresthesia.