Response rates according to the 1999 IWG criteria18 at the end of induction (primary end point), end of induction and maintenance, and best response rates
| Response status* . | End of induction (primary end point) (N = 100) . | End of induction and maintenance† (n = 96) . | Best response rates (N = 100) . |
|---|---|---|---|
| ORR‡ | 92 (92) [85-96] | 76 (79) [70-87] | 99 (99) [95-100] |
| CRR§ | 47 (47) [37-57] | 60 (63) [52-72] | 77 (77) [68-85] |
| CR | 20 (20) | 44 (46) | 51 (51) |
| CRu | 27 (27) | 16 (17) | 26 (26) |
| PR | 45 (45) | 16 (17) | 22 (22) |
| Stable disease | 1 (1) | 0 (0) | 0 (0) |
| Progressive disease | 2 (2) | 9 (9) | 1 (1) |
| Not evaluated | 5 (5) | 11 (11) | 0 (0) |
| Response status* . | End of induction (primary end point) (N = 100) . | End of induction and maintenance† (n = 96) . | Best response rates (N = 100) . |
|---|---|---|---|
| ORR‡ | 92 (92) [85-96] | 76 (79) [70-87] | 99 (99) [95-100] |
| CRR§ | 47 (47) [37-57] | 60 (63) [52-72] | 77 (77) [68-85] |
| CR | 20 (20) | 44 (46) | 51 (51) |
| CRu | 27 (27) | 16 (17) | 26 (26) |
| PR | 45 (45) | 16 (17) | 22 (22) |
| Stable disease | 1 (1) | 0 (0) | 0 (0) |
| Progressive disease | 2 (2) | 9 (9) | 1 (1) |
| Not evaluated | 5 (5) | 11 (11) | 0 (0) |
Data are presented as no. (%) [95% CI] or no. (%).
Patients without response assessment (due to whatever reason) were considered nonresponders.
Period of evaluation was after complete treatment of 74 patients (77%) and at premature withdrawal for 22 patients (23%).
ORR = (CR + CRu + PR).
CRR = (CR + Cru).