Multivariable analysis of risk factors associated with reporting no live birth after BMT
| Variables . | OR (95% CI) . |
|---|---|
| Age at first BMT (reference: <11y) | |
| 12-24 | 0.7 (0.33-1.54) |
| 25-34 | 0.8 (0.34-1.90) |
| >35 | 3.9 (1.32-11.80)† |
| Tried medical intervention to become pregnant (reference: yes) | |
| No* | 3.0 (1.96-4.76)† |
| Total body irradiation dose. cGy (reference: no TBI/low-intensity conditioning) | |
| 200-800 cGy TBI/low-intensity conditioning‡ | 1.3 (0.51-3.31) |
| No TBI/high-intensity conditioning‡ | 0.9 (0.47-1.65) |
| >800 cGy TBI/high-intensity conditioning‡ | 3.7 (1.91-7.00)† |
| Variables . | OR (95% CI) . |
|---|---|
| Age at first BMT (reference: <11y) | |
| 12-24 | 0.7 (0.33-1.54) |
| 25-34 | 0.8 (0.34-1.90) |
| >35 | 3.9 (1.32-11.80)† |
| Tried medical intervention to become pregnant (reference: yes) | |
| No* | 3.0 (1.96-4.76)† |
| Total body irradiation dose. cGy (reference: no TBI/low-intensity conditioning) | |
| 200-800 cGy TBI/low-intensity conditioning‡ | 1.3 (0.51-3.31) |
| No TBI/high-intensity conditioning‡ | 0.9 (0.47-1.65) |
| >800 cGy TBI/high-intensity conditioning‡ | 3.7 (1.91-7.00)† |
Adjusted for: grades 3 to 4 chronic health conditions, sex, race/ethnicity, diseases status, history of pre-BMT pelvic/testicular radiation, history of pre-BMT alkylating agents, history of seeking fertility assistance to facilitate pregnancy, age at study, and history of pre-BMT live birth.
Participants who did not seek fertility assistance by consulting a doctor or taking fertility-promoting medications.
Statistically significant differences between groups.
High-intensity conditioning = myeloablative intensity conditioning; low-intensity conditioning = nonmyeloablative/reduced-intensity conditioning.