Variants in BAX/BCL2 detected in flow sorted myeloid compartment (CD3-/CD19-) and CLL compartment (CD3-/CD19+) cells in patients on long-term venetoclax
| Patient . | Myeloid compartment (%) . | CLL compartment (%) . |
|---|---|---|
| CLL3 | BAX c.475-1G>A (45.5) BAX Arg94Glufs*39 (4.6) | BCL2 Gly101Val (27.3) BCL2 Arg107_Arg110dup† (8.4) BCL2 Arg107_Arg110dup‡ (6.4) |
| CLL16 | BAX Glu41Argfs*19 (24.0) BAX Arg37* (2.6) | BCL2 Ala113Gly (10.0) BCL2 Gly101Val (1.3) |
| CLL81 | BAX Glu41Argfs*19 (15.3) BAX Arg37* (0.9) | BCL2 Asp103Glu (20.0) |
| Patient . | Myeloid compartment (%) . | CLL compartment (%) . |
|---|---|---|
| CLL3 | BAX c.475-1G>A (45.5) BAX Arg94Glufs*39 (4.6) | BCL2 Gly101Val (27.3) BCL2 Arg107_Arg110dup† (8.4) BCL2 Arg107_Arg110dup‡ (6.4) |
| CLL16 | BAX Glu41Argfs*19 (24.0) BAX Arg37* (2.6) | BCL2 Ala113Gly (10.0) BCL2 Gly101Val (1.3) |
| CLL81 | BAX Glu41Argfs*19 (15.3) BAX Arg37* (0.9) | BCL2 Asp103Glu (20.0) |