Manifestations of non-CNS EMD in all subjects with-CNS EMD identifiable by FDG PET/CT imaging (N = 38) at presentation to our institution
| Patient . | Sites of non-CNS EMD identified on FDG PET/CT imaging . |
|---|---|
| 1 | Retroperitoneal lymph node |
| 2 | Scalp soft tissue, mesenteric, periaortic, retroperitoneal lymph nodes, right kidney, left kidney, liver |
| 3 | Liver |
| 4 | Right kidney, left kidney |
| 5 | Mesenteric, retroperitoneal lymph nodes, right kidney, left kidney, extrusion from vertebral bone marrow into psoas |
| 6 | Mesenteric, peritoneal lymph nodes, mediastinum, pericardium, pleura, intramuscular lesion |
| 7 | Orbital bone, parotid gland, cervical, supraclavicular, axillary, peritoneal lymph nodes, pancreas |
| 8a* | Temporal bone, subcutaneous tissue surrounding external auditory canal, cervical, supraclavicular lymph nodes, pancreas |
| 8b* | Thoracic neural foramen, lumbar neural foramen (vertebral bodies) |
| 9 | Right kidney, left kidney, pleura |
| 10 | Supraclavicular, mesenteric lymph nodes, pleura, left kidney |
| 11 | Parotid gland, maxillary sinus, cervical, supraclavicular, mesenteric lymph nodes, mediastinum, liver, stomach, scrotum |
| 12 | Breast, subcutaneous left lower extremity lesions, extrusion from right extremity bone marrow to surrounding soft tissue |
| 13 | Cervical, axillary, retroperitoneal, mesenteric, inguinal, pelvic lymph nodes, mediastinum, right kidney, left kidney, pancreas |
| 14 | Retroperitoneal, pelvic wall lymph nodes, pancreas, testes |
| 15 | Breast, cervical, axillary lymph nodes, mediastinum |
| 16 | Liver |
| 17 | Inguinal, pelvic wall, popliteal lymph nodes, deep thigh lymph nodes, skin (leukemia cutis), bone |
| 18 | Right kidney, left kidney, testes |
| 19 | Right kidney, left kidney, spleen, pancreas |
| 20 | Right kidney, left kidney, spleen |
| 21 | Testes |
| 22 | Maxillary sinus, right kidney |
| 23 | Inguinal lymph nodes, spleen |
| 24 | Mesenteric, retroperitoneal lymph nodes, mediastinum, right kidney, left kidney, spleen, pancreas |
| 25 | Breast, retroperitoneal lymph nodes, spleen, pancreas |
| 26 | Extrusion from sternum to surrounding soft tissues |
| 27 | Left kidney |
| 28 | Spleen |
| 29 | Pancreas |
| 30 | Right kidney, left kidney |
| 31 | Inguinal lymph node |
| 32 | Testes |
| 33 | Right kidney, left kidney, pleura |
| 34 | Right kidney, left kidney |
| 35 | Spleen |
| 36 | Skin (leukemia cutis) |
| 37 | Spleen |
| 38 | Mediastinum, right kidney, left kidney |
| Patient . | Sites of non-CNS EMD identified on FDG PET/CT imaging . |
|---|---|
| 1 | Retroperitoneal lymph node |
| 2 | Scalp soft tissue, mesenteric, periaortic, retroperitoneal lymph nodes, right kidney, left kidney, liver |
| 3 | Liver |
| 4 | Right kidney, left kidney |
| 5 | Mesenteric, retroperitoneal lymph nodes, right kidney, left kidney, extrusion from vertebral bone marrow into psoas |
| 6 | Mesenteric, peritoneal lymph nodes, mediastinum, pericardium, pleura, intramuscular lesion |
| 7 | Orbital bone, parotid gland, cervical, supraclavicular, axillary, peritoneal lymph nodes, pancreas |
| 8a* | Temporal bone, subcutaneous tissue surrounding external auditory canal, cervical, supraclavicular lymph nodes, pancreas |
| 8b* | Thoracic neural foramen, lumbar neural foramen (vertebral bodies) |
| 9 | Right kidney, left kidney, pleura |
| 10 | Supraclavicular, mesenteric lymph nodes, pleura, left kidney |
| 11 | Parotid gland, maxillary sinus, cervical, supraclavicular, mesenteric lymph nodes, mediastinum, liver, stomach, scrotum |
| 12 | Breast, subcutaneous left lower extremity lesions, extrusion from right extremity bone marrow to surrounding soft tissue |
| 13 | Cervical, axillary, retroperitoneal, mesenteric, inguinal, pelvic lymph nodes, mediastinum, right kidney, left kidney, pancreas |
| 14 | Retroperitoneal, pelvic wall lymph nodes, pancreas, testes |
| 15 | Breast, cervical, axillary lymph nodes, mediastinum |
| 16 | Liver |
| 17 | Inguinal, pelvic wall, popliteal lymph nodes, deep thigh lymph nodes, skin (leukemia cutis), bone |
| 18 | Right kidney, left kidney, testes |
| 19 | Right kidney, left kidney, spleen, pancreas |
| 20 | Right kidney, left kidney, spleen |
| 21 | Testes |
| 22 | Maxillary sinus, right kidney |
| 23 | Inguinal lymph nodes, spleen |
| 24 | Mesenteric, retroperitoneal lymph nodes, mediastinum, right kidney, left kidney, spleen, pancreas |
| 25 | Breast, retroperitoneal lymph nodes, spleen, pancreas |
| 26 | Extrusion from sternum to surrounding soft tissues |
| 27 | Left kidney |
| 28 | Spleen |
| 29 | Pancreas |
| 30 | Right kidney, left kidney |
| 31 | Inguinal lymph node |
| 32 | Testes |
| 33 | Right kidney, left kidney, pleura |
| 34 | Right kidney, left kidney |
| 35 | Spleen |
| 36 | Skin (leukemia cutis) |
| 37 | Spleen |
| 38 | Mediastinum, right kidney, left kidney |
8a and 8b represent a single patient who received 2 separate infusions of the same CAR product at initial treatment and subsequent disease recurrence.