Univariate and multivariable analysis of factors for OS in 400 PTCL ≥70 years with PTCL receiving multiagent treatment
| . | Univariate . | Multivariate . | ||
|---|---|---|---|---|
| Characteristic . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Age groups (70-74, 75-84, 85+) | 1.23 (1.02, 1.47) | .027 | 1.27 (1.06, 1.53) | .011 |
| 75-84 vs 70-74 | 1.27 (1.00, 1.61) | .049 | 1.38 (1.08, 1.77) | .011 |
| 85+ vs 70-74 | 1.20 (0.97, 1.49) | .095 | 1.21 (0.96, 1.52) | .103 |
| Ann Arbor stage III-IV (vs I-II) | 1.51 (1.15, 1.99) | .003 | 1.69 (1.26, 2.27) | <.001 |
| 1.12 (0.98, 1.29) | .093 | |||
| CCI = 1 vs CCI = 0 | 1.35 (1.00, 1.82) | .050 | 1.11 (0.82, 1.51) | .500 |
| CCI > 1 vs CCI = 0 | 1.39 (1.06, 1.81) | .016 | 1.25 (0.95, 1.64) | .109 |
| Subtypes of TCL | ||||
| ALCL vs AITL | 1.08 (0.74, 1.59) | .679 | 1.97 (1.24, 3.15) | .004 |
| EATL vs AITL | 1.26 (0.64, 2.51) | .507 | 1.36 (0.62, 2.97) | .448 |
| PTCL, NOS vs AITL | 1.56 (1.21, 2.02) | .001 | 1.87 (1.41, 2.48) | <.0001 |
| EATL vs ALCL | 1.16 (0.56, 2.41) | .688 | 1.01 (0.45, 2.24) | .984 |
| PTCL, NOS vs ALCL | 1.41 (0.99, 2.02) | .058 | 1.05 (0.72, 1.54) | .804 |
| PTCL, NOS vs EATL | 1.20 (0.61, 2.36) | .592 | 1.00 (0.50, 2.00) | .988 |
| Sex: male vs female | 1.14 (0.91, 1.43) | .266 | 1.02 (0.80, 1.29) | .905 |
| Location: California vs Sweden | 0.86 (0.67, 1.10) | .238 | 0.93 (0.72, 1.20) | .568 |
| . | Univariate . | Multivariate . | ||
|---|---|---|---|---|
| Characteristic . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Age groups (70-74, 75-84, 85+) | 1.23 (1.02, 1.47) | .027 | 1.27 (1.06, 1.53) | .011 |
| 75-84 vs 70-74 | 1.27 (1.00, 1.61) | .049 | 1.38 (1.08, 1.77) | .011 |
| 85+ vs 70-74 | 1.20 (0.97, 1.49) | .095 | 1.21 (0.96, 1.52) | .103 |
| Ann Arbor stage III-IV (vs I-II) | 1.51 (1.15, 1.99) | .003 | 1.69 (1.26, 2.27) | <.001 |
| 1.12 (0.98, 1.29) | .093 | |||
| CCI = 1 vs CCI = 0 | 1.35 (1.00, 1.82) | .050 | 1.11 (0.82, 1.51) | .500 |
| CCI > 1 vs CCI = 0 | 1.39 (1.06, 1.81) | .016 | 1.25 (0.95, 1.64) | .109 |
| Subtypes of TCL | ||||
| ALCL vs AITL | 1.08 (0.74, 1.59) | .679 | 1.97 (1.24, 3.15) | .004 |
| EATL vs AITL | 1.26 (0.64, 2.51) | .507 | 1.36 (0.62, 2.97) | .448 |
| PTCL, NOS vs AITL | 1.56 (1.21, 2.02) | .001 | 1.87 (1.41, 2.48) | <.0001 |
| EATL vs ALCL | 1.16 (0.56, 2.41) | .688 | 1.01 (0.45, 2.24) | .984 |
| PTCL, NOS vs ALCL | 1.41 (0.99, 2.02) | .058 | 1.05 (0.72, 1.54) | .804 |
| PTCL, NOS vs EATL | 1.20 (0.61, 2.36) | .592 | 1.00 (0.50, 2.00) | .988 |
| Sex: male vs female | 1.14 (0.91, 1.43) | .266 | 1.02 (0.80, 1.29) | .905 |
| Location: California vs Sweden | 0.86 (0.67, 1.10) | .238 | 0.93 (0.72, 1.20) | .568 |