Univariate and multivariable analysis of factors for OS in patients ≥70 years with PTCL
| . | Univariate . | Multivariate . | ||
|---|---|---|---|---|
| Variable . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Age groups (70-74, 75-84, 85+) | 1.42 (1.28, 1.59) | <.001 | 1.42 (1.26, 1.60) | <.001 |
| 75-84 vs 70-74 | 1.29 (1.08, 1.55) | .005 | 1.32 (1.09, 1.61) | .005 |
| 85+ vs 70-74 | 1.43 (1.29, 1.59) | <.001 | 1.41 (1.25, 1.58) | <.001 |
| Ann Arbor stage III-IV (vs I-II) | 1.58 (1.33, 1.87) | <.001 | 1.61 (1.34, 1.94) | <.001 |
| CCI | 1.23 (1.12, 1.34) | <.001 | 1.19 (1.08, 1.30) | <.001 |
| CCI = 1 vs CCI = 0 | 1.30 (1.05, 1.60) | .014 | 1.14 (0.92, 1.41) | .247 |
| CCI > 1 vs CCI = 0 | 1.49 (1.25, 1.79) | <.001 | 1.39 (1.15, 1.68) | .001 |
| Subtypes of TCL | .038 | .001 | ||
| ALCL vs AITL | 1.11 (0.86, 1.44) | .418 | 1.85 (1.35, 2.53) | <.001 |
| EATL vs AITL | 1.45 (0.96, 2.20) | .077 | 2.20 (1.23, 3.94) | .008 |
| PTCL, NOS vs AITL | 1.31 (1.09, 1.57) | .004 | 1.52 (1.24, 1.86) | <.001 |
| ENKTCL vs AITL | 0.88 (0.63, 1.25) | .481 | 1.52 (0.93, 2.47) | .095 |
| ENKTCL vs ALCL | 0.80 (0.55, 1.17) | .247 | 0.91 (0.58, 1.42) | .672 |
| ENKTCL vs EATL | 0.60 (0.37, 0.99) | .045 | 0.41 (0.21, 0.81) | .011 |
| ENKTCL vs PTCL, NOS | 0.68 (0.49, 0.95) | 0.023 | 0.74 (0.50, 1.10) | .134 |
| EATL vs ALCL | 1.28 (0.82, 1.98) | 0.276 | 1.44 (0.82, 2.53) | .201 |
| PTCL, NOS vs ALCL | 1.16 (0.92, 1.46) | 0.225 | 1.00 (0.77, 1.30) | .978 |
| PTCL, NOS vs EATL | 0.90 (0.60, 1.34) | 0.590 | 0.71 (0.43, 1.16) | .168 |
| Treatment (yes vs no) | 0.65 (0.56, 0.75) | <0.001 | 0.58 (0.48, 0.70) | <.001 |
| Multiagent (yes vs no) | 0.69 (0.60, 0.81) | <0.001 | 0.70 (0.58, 0.83) | <.001 |
| Sex: male vs female | 0.99 (0.86, 1.15) | 0.932 | 0.97 (0.82, 1.14) | .702 |
| CCR vs SLR | 1.04 (0.86, 1.25) | 0.702 | 1.18 (0.96, 1.45) | .123 |
| . | Univariate . | Multivariate . | ||
|---|---|---|---|---|
| Variable . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Age groups (70-74, 75-84, 85+) | 1.42 (1.28, 1.59) | <.001 | 1.42 (1.26, 1.60) | <.001 |
| 75-84 vs 70-74 | 1.29 (1.08, 1.55) | .005 | 1.32 (1.09, 1.61) | .005 |
| 85+ vs 70-74 | 1.43 (1.29, 1.59) | <.001 | 1.41 (1.25, 1.58) | <.001 |
| Ann Arbor stage III-IV (vs I-II) | 1.58 (1.33, 1.87) | <.001 | 1.61 (1.34, 1.94) | <.001 |
| CCI | 1.23 (1.12, 1.34) | <.001 | 1.19 (1.08, 1.30) | <.001 |
| CCI = 1 vs CCI = 0 | 1.30 (1.05, 1.60) | .014 | 1.14 (0.92, 1.41) | .247 |
| CCI > 1 vs CCI = 0 | 1.49 (1.25, 1.79) | <.001 | 1.39 (1.15, 1.68) | .001 |
| Subtypes of TCL | .038 | .001 | ||
| ALCL vs AITL | 1.11 (0.86, 1.44) | .418 | 1.85 (1.35, 2.53) | <.001 |
| EATL vs AITL | 1.45 (0.96, 2.20) | .077 | 2.20 (1.23, 3.94) | .008 |
| PTCL, NOS vs AITL | 1.31 (1.09, 1.57) | .004 | 1.52 (1.24, 1.86) | <.001 |
| ENKTCL vs AITL | 0.88 (0.63, 1.25) | .481 | 1.52 (0.93, 2.47) | .095 |
| ENKTCL vs ALCL | 0.80 (0.55, 1.17) | .247 | 0.91 (0.58, 1.42) | .672 |
| ENKTCL vs EATL | 0.60 (0.37, 0.99) | .045 | 0.41 (0.21, 0.81) | .011 |
| ENKTCL vs PTCL, NOS | 0.68 (0.49, 0.95) | 0.023 | 0.74 (0.50, 1.10) | .134 |
| EATL vs ALCL | 1.28 (0.82, 1.98) | 0.276 | 1.44 (0.82, 2.53) | .201 |
| PTCL, NOS vs ALCL | 1.16 (0.92, 1.46) | 0.225 | 1.00 (0.77, 1.30) | .978 |
| PTCL, NOS vs EATL | 0.90 (0.60, 1.34) | 0.590 | 0.71 (0.43, 1.16) | .168 |
| Treatment (yes vs no) | 0.65 (0.56, 0.75) | <0.001 | 0.58 (0.48, 0.70) | <.001 |
| Multiagent (yes vs no) | 0.69 (0.60, 0.81) | <0.001 | 0.70 (0.58, 0.83) | <.001 |
| Sex: male vs female | 0.99 (0.86, 1.15) | 0.932 | 0.97 (0.82, 1.14) | .702 |
| CCR vs SLR | 1.04 (0.86, 1.25) | 0.702 | 1.18 (0.96, 1.45) | .123 |