Apitopes P1 and P17 bind common human HLA-DRB1* molecules
| . | HLA-DRA*01:01; DRB1*15:01 . | HLA-DRA*01:01; DRB1*03:01 . | HLA-DRA*01:01; DRB1*04:01 . | HLA-DRA*01:01; DRB1*11:01 . |
|---|---|---|---|---|
| P1 | 0.06 | 32.21 | 0.40 | 1.28 |
| P17 | 0.04 | 21.90 | 5.09 | 4.19 |
| . | HLA-DRA*01:01; DRB1*15:01 . | HLA-DRA*01:01; DRB1*03:01 . | HLA-DRA*01:01; DRB1*04:01 . | HLA-DRA*01:01; DRB1*11:01 . |
|---|---|---|---|---|
| P1 | 0.06 | 32.21 | 0.40 | 1.28 |
| P17 | 0.04 | 21.90 | 5.09 | 4.19 |
Data are IC50 (µM).
Affinity binding of apitopes P1 and P17 to the indicated MHC alleles, as determined using an in vitro MHC binding assay (ProImmune REVEAL assay) studying displacement of a control peptide by apitopes P1 and P17.