Table 4.

HRU: PS-matched alloHSCT-NIPC patients and alloHSCT non-NIPC patients

AlloHSCT-NIPC patients (years 1,2)AlloHSCT non-NIPC patients (years 1,2)
Year −1Year 1Year 2Year −1Year 1Year 2
n = 155n = 155n = 73n = 155n = 155n = 74
Patients with 1+ hospital admission, n (%) 127 (82%) 149 (96%)*** 39(53%)** 124 (80%) 145 (94%)*** 24 (32%)** 
Number of inpatient admissions, per patient, mean ± SD 3.0 ± 2.8 3.8 ± 3.2*** 1.7 ± 2.7* 3.0 ± 2.5 2.6 ± 2.4*** .7 ± 1.5* 
Length of stay per admission (days), mean ± SD 38.4 ± 36.3 68.7 ± 109.7** 26.2 ± 37.5 42.3 ± 34.9 41.5 ± 46.3** 23.9 ± 32.4 
Annual number of outpatient visits per patient, mean ± SD 
 Physician office visits 24.6 ± 20.7 24.8 ± 21.8 23.4 ± 19.4*** 25.4 ± 20.3 24.2 ± 21.5 13.9 ± 12.5*** 
 Outpatient hospital visits 35.1 ± 20.0 55.6 ± 31.0** 30.1 ± 24.7*** 33.3 ± 20.8 44.8 ± 28.9** 17.0 ± 14.6*** 
 ED visits 1.0 ± 1.4 1.4 ± 3.6 .8 ± 1.5 1.2 ± 2.0 1.0 ± 2.6 .5 ± 1.0 
 Number of pulmonary function test dates of any kind‡ 2.6 ± 1.5 3.0 ± 3.5*** 3.7 ± 4.0*** 2.6 ± 1.7 2.1 ± 2.5*** 1.5 ± 2.5*** 
 Number of days with 1+ treatments of any kind .9 ± .8 2.3 ± 4.5 4.1 ± 8.0** 0.8 ± 0.9 1.2 ± 2.4 .7 ± 2.4** 
Annual number of administrations or prescription fills per patient, mean ± SD 
 Chemotherapy 6.9 ± 9.4 1.8 ± 3.4 1.2 ± 3.6 7.9 ± 11.1 2.8 ± 6.6 1.2 ± 3.3 
 Immunosuppressive agents .5 ± 2.6 8.0 ± 7.8 5.8 ± 6.5 0.7 ± 2.9 7.8 ± 8.3 4.3 ± 6.9 
 Antifungals .5 ± 3.4 1.8 ± 5.7 .6 ± 2.2 0.4 ± 2.2 1.7 ± 6.9 .4 ± 2.4 
 Antibiotics 3.4 ± 3.1 5.1 ± 4.7 6.0 ± 5.4 3.4 ± 3.0 5.0 ± 4.8 3.4 ± 3.9 
 Antivirals 1.8 ± 2.6 8.9 ± 5.8 6.1 ± 4.8 2.5 ± 2.9 9.3 ± 5.3 6.1 ± 4.7 
AlloHSCT-NIPC patients (years 1,2)AlloHSCT non-NIPC patients (years 1,2)
Year −1Year 1Year 2Year −1Year 1Year 2
n = 155n = 155n = 73n = 155n = 155n = 74
Patients with 1+ hospital admission, n (%) 127 (82%) 149 (96%)*** 39(53%)** 124 (80%) 145 (94%)*** 24 (32%)** 
Number of inpatient admissions, per patient, mean ± SD 3.0 ± 2.8 3.8 ± 3.2*** 1.7 ± 2.7* 3.0 ± 2.5 2.6 ± 2.4*** .7 ± 1.5* 
Length of stay per admission (days), mean ± SD 38.4 ± 36.3 68.7 ± 109.7** 26.2 ± 37.5 42.3 ± 34.9 41.5 ± 46.3** 23.9 ± 32.4 
Annual number of outpatient visits per patient, mean ± SD 
 Physician office visits 24.6 ± 20.7 24.8 ± 21.8 23.4 ± 19.4*** 25.4 ± 20.3 24.2 ± 21.5 13.9 ± 12.5*** 
 Outpatient hospital visits 35.1 ± 20.0 55.6 ± 31.0** 30.1 ± 24.7*** 33.3 ± 20.8 44.8 ± 28.9** 17.0 ± 14.6*** 
 ED visits 1.0 ± 1.4 1.4 ± 3.6 .8 ± 1.5 1.2 ± 2.0 1.0 ± 2.6 .5 ± 1.0 
 Number of pulmonary function test dates of any kind‡ 2.6 ± 1.5 3.0 ± 3.5*** 3.7 ± 4.0*** 2.6 ± 1.7 2.1 ± 2.5*** 1.5 ± 2.5*** 
 Number of days with 1+ treatments of any kind .9 ± .8 2.3 ± 4.5 4.1 ± 8.0** 0.8 ± 0.9 1.2 ± 2.4 .7 ± 2.4** 
Annual number of administrations or prescription fills per patient, mean ± SD 
 Chemotherapy 6.9 ± 9.4 1.8 ± 3.4 1.2 ± 3.6 7.9 ± 11.1 2.8 ± 6.6 1.2 ± 3.3 
 Immunosuppressive agents .5 ± 2.6 8.0 ± 7.8 5.8 ± 6.5 0.7 ± 2.9 7.8 ± 8.3 4.3 ± 6.9 
 Antifungals .5 ± 3.4 1.8 ± 5.7 .6 ± 2.2 0.4 ± 2.2 1.7 ± 6.9 .4 ± 2.4 
 Antibiotics 3.4 ± 3.1 5.1 ± 4.7 6.0 ± 5.4 3.4 ± 3.0 5.0 ± 4.8 3.4 ± 3.9 
 Antivirals 1.8 ± 2.6 8.9 ± 5.8 6.1 ± 4.8 2.5 ± 2.9 9.3 ± 5.3 6.1 ± 4.7 

This table shows the mean costs for matched alloHSCT patients (NIPC vs non-NIPC) in the follow-up years 1 and 2 compared with the period before transplant.

Years 3 through 5 in supplemental Materials.

Pulmonary function test includes spirometry, lung function volume, lung diffusion capacity, and plethysmography.

*

P value ≤ .05; **P value ≤ .01; ***P value ≤ .001.

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