Univariable analysis
| . | KMT2A (n = 426) . | Intermediate (n = 2384) . | Adverse (n = 969) . | . | |||
|---|---|---|---|---|---|---|---|
| Outcomes, y . | n . | Prob, % (95% CI) . | n . | Prob, % (95% CI) . | n . | Prob, % (95% CI) . | P . |
| Relapse | 426 | 2383 | 968 | <.001 | |||
| 1 | 225 | 25 (21-30) | 1292 | 24 (22-26) | 433 | 34 (31-37) | <.001 |
| 3 | 115 | 34 (30-39) | 660 | 31 (29-33) | 198 | 44 (40-47) | <.001 |
| 5 | 74 | 37 (32-42) | 393 | 33 (31-35) | 128 | 46 (42-49) | <.001 |
| NRM | 426 | 2383 | 968 | .411 | |||
| 1 | 225 | 16 (13-20) | 1292 | 14 (13-16) | 433 | 17 (14-19) | .295 |
| 3 | 115 | 23 (19-28) | 660 | 20 (18-22) | 198 | 23 (21-26) | .070 |
| 5 | 74 | 25 (21-29) | 393 | 24 (22-26) | 128 | 25 (22-28) | .801 |
| LFS | 426 | 2383 | 968 | <.001 | |||
| 1 | 223 | 59 (54-63) | 1284 | 62 (60-64) | 431 | 49 (46-53) | <.001 |
| 3 | 114 | 43 (38-48) | 659 | 49 (47-52) | 197 | 33 (30-36) | <.001 |
| 5 | 73 | 38 (33-44) | 393 | 43 (41-46) | 127 | 30 (27-33) | <.001 |
| OS | 426 | 2384 | 969 | <.001 | |||
| 1 | 259 | 68 (63-72) | 1472 | 70 (68-72) | 521 | 60 (57-63) | <.001 |
| 3 | 119 | 45 (40-51) | 748 | 55 (53-57) | 225 | 38 (35-41) | <.001 |
| 5 | 79 | 42 (37-48) | 443 | 48 (46-50) | 141 | 34 (30-37) | <.001 |
| . | KMT2A (n = 426) . | Intermediate (n = 2384) . | Adverse (n = 969) . | . | |||
|---|---|---|---|---|---|---|---|
| Outcomes, y . | n . | Prob, % (95% CI) . | n . | Prob, % (95% CI) . | n . | Prob, % (95% CI) . | P . |
| Relapse | 426 | 2383 | 968 | <.001 | |||
| 1 | 225 | 25 (21-30) | 1292 | 24 (22-26) | 433 | 34 (31-37) | <.001 |
| 3 | 115 | 34 (30-39) | 660 | 31 (29-33) | 198 | 44 (40-47) | <.001 |
| 5 | 74 | 37 (32-42) | 393 | 33 (31-35) | 128 | 46 (42-49) | <.001 |
| NRM | 426 | 2383 | 968 | .411 | |||
| 1 | 225 | 16 (13-20) | 1292 | 14 (13-16) | 433 | 17 (14-19) | .295 |
| 3 | 115 | 23 (19-28) | 660 | 20 (18-22) | 198 | 23 (21-26) | .070 |
| 5 | 74 | 25 (21-29) | 393 | 24 (22-26) | 128 | 25 (22-28) | .801 |
| LFS | 426 | 2383 | 968 | <.001 | |||
| 1 | 223 | 59 (54-63) | 1284 | 62 (60-64) | 431 | 49 (46-53) | <.001 |
| 3 | 114 | 43 (38-48) | 659 | 49 (47-52) | 197 | 33 (30-36) | <.001 |
| 5 | 73 | 38 (33-44) | 393 | 43 (41-46) | 127 | 30 (27-33) | <.001 |
| OS | 426 | 2384 | 969 | <.001 | |||
| 1 | 259 | 68 (63-72) | 1472 | 70 (68-72) | 521 | 60 (57-63) | <.001 |
| 3 | 119 | 45 (40-51) | 748 | 55 (53-57) | 225 | 38 (35-41) | <.001 |
| 5 | 79 | 42 (37-48) | 443 | 48 (46-50) | 141 | 34 (30-37) | <.001 |
NE, nonevaluable; Prob, probability.