Summary statistics of total study cohort (n = 373)
| Patient demographics . | Entire cohort (n = 373), % . |
|---|---|
| Age at study entry (y) | |
| <1 | 218 (59) |
| 1-5 | 78 (24) |
| 5-12 | 48 (11) |
| >12 | 29 (7) |
| Sex | |
| Male | 203 (54) |
| Female | 170 (46) |
| Race | |
| White | 182 (49) |
| Black | 95 (25) |
| Asian | 16 (4) |
| Other | 80 (21) |
| Follow-up time (d) | |
| Median (IQR 25-75) | 688 (158-1271) |
| Total additional CVCs | |
| 0 | 134 (36) |
| 1 | 102 (27) |
| 2 | 63 (17) |
| 3 | 34 (9) |
| 4 or more | 40 (11) |
| Chronic medical condition | |
| Congenital heart disease | 68 (18) |
| Total parenteral nutrition dependence | 54 (14) |
| Cancer | 30 (8) |
| Renal disease | 23 (6) |
| Hyperinsulinemia | 24 (6) |
| Cystic fibrosis | 6 (2) |
| Autoimmune disease | 4 (1) |
| Gastrointestinal autoimmune disease | 10 (3) |
| Sickle cell disease | 8 (2) |
| Other | 213 (57) |
| None | 45 (12) |
| Congenital thrombophilia* | |
| Present | 36 (10) |
| Absent | 203 (54) |
| Not Assessed | 134 (36) |
| Acute prothrombotic condition | |
| Recent surgery (<30 d) | 78 (21) |
| Active infection | 71 (19) |
| Protein-losing process | 11 (3) |
| Prothrombotic medication | 11 (3) |
| Index CVC type | |
| Peripherally inserted central catheter | 219 (59) |
| Tunneled catheter | 19 (5) |
| Nontunneled catheter | 135 (3) |
| Patient demographics . | Entire cohort (n = 373), % . |
|---|---|
| Age at study entry (y) | |
| <1 | 218 (59) |
| 1-5 | 78 (24) |
| 5-12 | 48 (11) |
| >12 | 29 (7) |
| Sex | |
| Male | 203 (54) |
| Female | 170 (46) |
| Race | |
| White | 182 (49) |
| Black | 95 (25) |
| Asian | 16 (4) |
| Other | 80 (21) |
| Follow-up time (d) | |
| Median (IQR 25-75) | 688 (158-1271) |
| Total additional CVCs | |
| 0 | 134 (36) |
| 1 | 102 (27) |
| 2 | 63 (17) |
| 3 | 34 (9) |
| 4 or more | 40 (11) |
| Chronic medical condition | |
| Congenital heart disease | 68 (18) |
| Total parenteral nutrition dependence | 54 (14) |
| Cancer | 30 (8) |
| Renal disease | 23 (6) |
| Hyperinsulinemia | 24 (6) |
| Cystic fibrosis | 6 (2) |
| Autoimmune disease | 4 (1) |
| Gastrointestinal autoimmune disease | 10 (3) |
| Sickle cell disease | 8 (2) |
| Other | 213 (57) |
| None | 45 (12) |
| Congenital thrombophilia* | |
| Present | 36 (10) |
| Absent | 203 (54) |
| Not Assessed | 134 (36) |
| Acute prothrombotic condition | |
| Recent surgery (<30 d) | 78 (21) |
| Active infection | 71 (19) |
| Protein-losing process | 11 (3) |
| Prothrombotic medication | 11 (3) |
| Index CVC type | |
| Peripherally inserted central catheter | 219 (59) |
| Tunneled catheter | 19 (5) |
| Nontunneled catheter | 135 (3) |
Congenital thrombophilia defined as factor V Leiden mutation, antithrombin deficiency, protein C deficiency, protein S deficiency, and/or prothrombin gene mutation.