Table 3.

Clinical and hematologic characteristics of patients with ES according to death occurrence

Alive
(n = 93)
Dead
(n = 23)
Demographics   
 Age, y 46.7 (1.9-84.6) 71.4 (18.3-94.8)* 
 Sex   
  Male 45 (48) 11 (48) 
  Female 48 (52) 12 (52) 
Laboratory values   
 Hb, g/dL 8.9 (2.8-17.0) 6.6 (3.0-13.3)** 
 PLTs, × 109/L 19 (1-564) 39 (2-727) 
 ANC, × 109/L 2.50 (0.2-15.2) 3.1 (0.25-9.0) 
 LDH, ×ULN 1.6 (0.52-11.11) 2 (1-16) 
 IgG, g/dL 955 (52-5660) 1052 (340-1618) 
 IgA, g/dL 143 (24-1257) 165 (65-260) 
 IgM, g/dL 95 (10-1800) 82 (39-218) 
 DAT+ 82 (88) 21 (91) 
  IgG 53 (65) 11 (52) 
  IgG + C 20 (24) 5 (24) 
  C 5 (6) 0 (0) 
  Mixed 4 (5) 3 (14)*** 
  Atypical // 2 (10)*** 
 Positive antiplatelets (n = 38) 32 (84) 9 (82) 
 Positive antineutrophils (n = 22) 10 (45) 1 (20) 
Complications   
 Infection 27 (29) 12 (52) 
 Thrombosis 18 (19) 7 (30) 
Alive
(n = 93)
Dead
(n = 23)
Demographics   
 Age, y 46.7 (1.9-84.6) 71.4 (18.3-94.8)* 
 Sex   
  Male 45 (48) 11 (48) 
  Female 48 (52) 12 (52) 
Laboratory values   
 Hb, g/dL 8.9 (2.8-17.0) 6.6 (3.0-13.3)** 
 PLTs, × 109/L 19 (1-564) 39 (2-727) 
 ANC, × 109/L 2.50 (0.2-15.2) 3.1 (0.25-9.0) 
 LDH, ×ULN 1.6 (0.52-11.11) 2 (1-16) 
 IgG, g/dL 955 (52-5660) 1052 (340-1618) 
 IgA, g/dL 143 (24-1257) 165 (65-260) 
 IgM, g/dL 95 (10-1800) 82 (39-218) 
 DAT+ 82 (88) 21 (91) 
  IgG 53 (65) 11 (52) 
  IgG + C 20 (24) 5 (24) 
  C 5 (6) 0 (0) 
  Mixed 4 (5) 3 (14)*** 
  Atypical // 2 (10)*** 
 Positive antiplatelets (n = 38) 32 (84) 9 (82) 
 Positive antineutrophils (n = 22) 10 (45) 1 (20) 
Complications   
 Infection 27 (29) 12 (52) 
 Thrombosis 18 (19) 7 (30) 

Demographics and laboratory data reflect those collected at disease onset. Values are given as median (range) or n (%).

LDH, lactate dehydrogenase; ULN, upper limit of normal.

*

P = .001, **P < .05, ***P = .01.

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