Thresholds for coagulation parameters prior to high-risk procedures in patients with CLD
| Characteristic . | AASLD 202120 . | ACG 202037 . | AGA 201935 . | SIR 201936 . |
|---|---|---|---|---|
| PT/INR | Do not correct | Do not correct | Do not correct | INR >2.5* |
| Platelet count | Do not correct | >50 × 109/L | >50 × 109/L | >30 × 109/L |
| Fibrinogen | Do not correct | No specific recommendation | >1.2 g/L | >1 g/L |
| VHA | Do not use routinely | May be useful | No specific recommendation | No specific recommendation |
| Characteristic . | AASLD 202120 . | ACG 202037 . | AGA 201935 . | SIR 201936 . |
|---|---|---|---|---|
| PT/INR | Do not correct | Do not correct | Do not correct | INR >2.5* |
| Platelet count | Do not correct | >50 × 109/L | >50 × 109/L | >30 × 109/L |
| Fibrinogen | Do not correct | No specific recommendation | >1.2 g/L | >1 g/L |
| VHA | Do not use routinely | May be useful | No specific recommendation | No specific recommendation |
Give vitamin K if INR >2.5; do not use FFP/prothrombin complex concentrate.
Table adapted from Northup et al20 with permission from Wiley.
AASLD, American Association for the Study of Liver Disease; ACG, American College of Gastroenterology; AGA, American Gastroenterology Association; SIR, Society of Interventional Radiology; VHA, viscoelastic hemostatic assay.