Laboratory evaluation of neutropenia by age
| Neonates . | Infants/children . | Adolescents and young adults . | Adults . |
|---|---|---|---|
| Recommended for all patients | |||
| CBC with differential Liver and renal function Peripheral blood smear | CBC with differential Liver and renal function Peripheral blood smear | CBC with differential Liver and renal function Peripheral blood smear | CBC with differential Liver and renal function Peripheral blood smear HIV antibody screening T-LGL flow cytometry |
| To be considered based on patient-specific history | |||
| Maternal antineutrophil antibodies | Antineutrophil antibodies Vitamin B12, folate, copper Amylase isoenzymes Fecal elastase Telomere length Chromosomal breakage ADA2 enzyme activity IgG/A/M/E T/B/NK subsets | Vitamin B12, folate, copper HIV Urine drug screen Amylase isoenzymes Fecal elastase Telomere length Chromosomal breakage ADA2 enzyme activity ANA, ESR, CRP IgG/A/M/E T/B/NK subsets | Vitamin B12, folate, copper Urine drug screen ANA, rheumatoid factor ESR, CRP Amylase isoenzymes Fecal elastase Telomere length Chromosomal breakage ADA2 enzyme activity IgG/A/M/E T/B/NK subsets |
| Neonates . | Infants/children . | Adolescents and young adults . | Adults . |
|---|---|---|---|
| Recommended for all patients | |||
| CBC with differential Liver and renal function Peripheral blood smear | CBC with differential Liver and renal function Peripheral blood smear | CBC with differential Liver and renal function Peripheral blood smear | CBC with differential Liver and renal function Peripheral blood smear HIV antibody screening T-LGL flow cytometry |
| To be considered based on patient-specific history | |||
| Maternal antineutrophil antibodies | Antineutrophil antibodies Vitamin B12, folate, copper Amylase isoenzymes Fecal elastase Telomere length Chromosomal breakage ADA2 enzyme activity IgG/A/M/E T/B/NK subsets | Vitamin B12, folate, copper HIV Urine drug screen Amylase isoenzymes Fecal elastase Telomere length Chromosomal breakage ADA2 enzyme activity ANA, ESR, CRP IgG/A/M/E T/B/NK subsets | Vitamin B12, folate, copper Urine drug screen ANA, rheumatoid factor ESR, CRP Amylase isoenzymes Fecal elastase Telomere length Chromosomal breakage ADA2 enzyme activity IgG/A/M/E T/B/NK subsets |
T/B/NK, T cell/B cell/natural killer cell.