Assays used for fusion detection were Archer or next generation sequencing (NGS) methods. Archer (Heme fusion assay) is a custom-targeted anchored multiplex PCR-based RNA-seq assay for gene fusion detection. Fusions from RNA-seq or WGS were discovered by STAR-Fusion19 followed by manual inspection by WGS/RNA-Seq reads. Survival is reported in months from date of diagnosis to date of death (or hematopoietic stem cell transplant). Race: A, Asian; AA, African American; C, Caucasian; M, Middle Eastern; H, Hispanic. Status: AWD, alive with disease; AWOD, alive without disease; DOC, died of other cause; DOD, died of disease. Skin involvement: E, extremities; G, genitals; HN, head/neck; O, oral mucosa; T, trunk. Epidermis density is described as 0, very low epidermal infiltrate density of the lymphoma cells; 1, low epidermal density of lymphoma cells; 2, intermediate density of lymphoma cells; 3, high density of lymphoma cells.

M, mixed features, describing a histological pattern that have features of mycosis fungoides (MF), such as Pautrier microabscesses or lichenoid infiltrates; N, Neurotropism, neural invasion of lymphoid infiltrates NEG, negative for expression determined by immunohistochemistry (IHC); P, pagetoid, describing a pattern of lymphocytic infiltration where it is densest at the basal layer, and infiltration density becomes less sparse, but still present, at the top layer of the epidermis; POS, positive for expression determined by IHC; SUBSET, a subset of the population was positive for expression determined by IHC; TCR, T-cell receptor; VAR, variable expression determined by IHC.

Hematopoietic stem cell transplant.