Table 4. ORs with 95% CIs for VTE across... | American Society of Hematology

Table 4.

ORs with 95% CIs for VTE across tertiles of plasma VWF and categories of platelet count

Platelet count, ×10⁹/L	VWF, %	Controls (n = 816)	Cases (n = 403)	Within stratum, OR (95% CI)		Combined effects, OR (95% CI)
Platelet count, ×10⁹/L	VWF, %	Controls (n = 816)	Cases (n = 403)	Model 1*	Model 2†	Model 1*	Model 2†
<230		349	176
	T1	112	41	Ref	Ref	Ref	Ref
	T2	112	64	1.56 (0.97-2.51)	1.44 (0.84-2.45)	1.57 (0.98-2.52)	1.52 (0.90-2.59)
	T3	125	71	1.52 (0.95-2.44)	1.13 (0.66-1.95)	1.56 (0.98-2.49)	1.28 (0.76-2.17)
	P for trend			.1	.7
230-299		349	157
	T1	111	49	Ref	Ref	1.22 (0.74-1.99)	1.04 (0.60-1.82)
	T2	117	52	1.01 (0.63-1.61)	1.06 (0.62-1.83)	1.22 (0.75-1.99)	1.09 (0.63-1.90)
	T3	121	56	1.03 (0.64-1.64)	1.17 (0.69-2.00)	1.29 (0.80-2.08)	1.23 (0.71-2.10)
	P for trend			.9	.6
≥300		118	70
	T1	50	24	Ref	Ref	1.30 (0.71-2.39)	1.18 (0.59-2.33)
	T2	44	21	1.09 (0.53-2.27)	1.30 (0.54-3.13)	1.32 (0.70-2.48)	1.34 (0.64-2.83)
	T3	24	25	2.77 (1.25-6.14)	2.52 (0.95-6.69)	2.91 (1.49-5.67)	2.40 (1.08-5.34)
	P for trend			.017	.073

Platelet count, ×10⁹/L	VWF, %	Controls (n = 816)	Cases (n = 403)	Within stratum, OR (95% CI)		Combined effects, OR (95% CI)
Platelet count, ×10⁹/L	VWF, %	Controls (n = 816)	Cases (n = 403)	Model 1*	Model 2†	Model 1*	Model 2†
<230		349	176
	T1	112	41	Ref	Ref	Ref	Ref
	T2	112	64	1.56 (0.97-2.51)	1.44 (0.84-2.45)	1.57 (0.98-2.52)	1.52 (0.90-2.59)
	T3	125	71	1.52 (0.95-2.44)	1.13 (0.66-1.95)	1.56 (0.98-2.49)	1.28 (0.76-2.17)
	P for trend			.1	.7
230-299		349	157
	T1	111	49	Ref	Ref	1.22 (0.74-1.99)	1.04 (0.60-1.82)
	T2	117	52	1.01 (0.63-1.61)	1.06 (0.62-1.83)	1.22 (0.75-1.99)	1.09 (0.63-1.90)
	T3	121	56	1.03 (0.64-1.64)	1.17 (0.69-2.00)	1.29 (0.80-2.08)	1.23 (0.71-2.10)
	P for trend			.9	.6
≥300		118	70
	T1	50	24	Ref	Ref	1.30 (0.71-2.39)	1.18 (0.59-2.33)
	T2	44	21	1.09 (0.53-2.27)	1.30 (0.54-3.13)	1.32 (0.70-2.48)	1.34 (0.64-2.83)
	T3	24	25	2.77 (1.25-6.14)	2.52 (0.95-6.69)	2.91 (1.49-5.67)	2.40 (1.08-5.34)
	P for trend			.017	.073

T, tertile.

Adjusted for age and sex.

Adjusted for age, sex, BMI, CRP, smoking, hypertension, estrogen use, self-reported history of cancer at baseline, and MPV.