ORs with 95% CIs for VTE across tertiles of plasma VWF and categories of MPV
| MPV, fL . | VWF, % . | Controls (n = 816) . | Cases (n = 403) . | Within stratum, OR (95% CI) . | Combined effects, OR (95% CI) . | ||
|---|---|---|---|---|---|---|---|
| Model 1* . | Model 2† . | Model 1* . | Model 2† . | ||||
| <8.5 | 314 | 148 | |||||
| T1 | 112 | 46 | Ref | Ref | Ref | Ref | |
| T2 | 106 | 54 | 1.27 (0.79-2.05) | 1.42 (0.81-2.48) | 1.25 (0.78-2.01) | 1.32 (0.77-2.27) | |
| T3 | 96 | 48 | 1.31 (0.80-2.17) | 1.40 (0.77-2.54) | 1.24 (0.76-2.03) | 1.25 (0.70-2.24) | |
| P for trend | .3 | .3 | |||||
| 8.5-9.5 | 324 | 163 | |||||
| T1 | 99 | 47 | Ref | Ref | 1.16 (0.71-1.90) | 1.16 (0.67-2.02) | |
| T2 | 107 | 57 | 1.12 (0.70-1.81) | 1.33 (0.77-2.27) | 1.31 (0.82-2.11) | 1.48 (0.85-2.58) | |
| T3 | 118 | 59 | 1.05 (0.65-1.69) | 0.97 (0.57-1.65) | 1.24 (0.77-1.98) | 1.11 (0.64-1.91) | |
| P for trend | .9 | .9 | |||||
| ≥9.5 | 178 | 92 | |||||
| T1 | 62 | 21 | Ref | Ref | 0.84 (0.46-1.53) | 0.85 (0.42-1.72) | |
| T2 | 60 | 26 | 1.24 (0.63-2.45) | 1.08 (0.49-2.41) | 1.07 (0.60-1.90) | 0.95 (0.48-1.90) | |
| T3 | 56 | 45 | 2.18 (1.15-4.16) | 2.16 (1.01-4.60) | 1.98 (1.17-3.36) | 2.10 (1.11-3.98) | |
| P for trend | .014 | .041 | |||||
| MPV, fL . | VWF, % . | Controls (n = 816) . | Cases (n = 403) . | Within stratum, OR (95% CI) . | Combined effects, OR (95% CI) . | ||
|---|---|---|---|---|---|---|---|
| Model 1* . | Model 2† . | Model 1* . | Model 2† . | ||||
| <8.5 | 314 | 148 | |||||
| T1 | 112 | 46 | Ref | Ref | Ref | Ref | |
| T2 | 106 | 54 | 1.27 (0.79-2.05) | 1.42 (0.81-2.48) | 1.25 (0.78-2.01) | 1.32 (0.77-2.27) | |
| T3 | 96 | 48 | 1.31 (0.80-2.17) | 1.40 (0.77-2.54) | 1.24 (0.76-2.03) | 1.25 (0.70-2.24) | |
| P for trend | .3 | .3 | |||||
| 8.5-9.5 | 324 | 163 | |||||
| T1 | 99 | 47 | Ref | Ref | 1.16 (0.71-1.90) | 1.16 (0.67-2.02) | |
| T2 | 107 | 57 | 1.12 (0.70-1.81) | 1.33 (0.77-2.27) | 1.31 (0.82-2.11) | 1.48 (0.85-2.58) | |
| T3 | 118 | 59 | 1.05 (0.65-1.69) | 0.97 (0.57-1.65) | 1.24 (0.77-1.98) | 1.11 (0.64-1.91) | |
| P for trend | .9 | .9 | |||||
| ≥9.5 | 178 | 92 | |||||
| T1 | 62 | 21 | Ref | Ref | 0.84 (0.46-1.53) | 0.85 (0.42-1.72) | |
| T2 | 60 | 26 | 1.24 (0.63-2.45) | 1.08 (0.49-2.41) | 1.07 (0.60-1.90) | 0.95 (0.48-1.90) | |
| T3 | 56 | 45 | 2.18 (1.15-4.16) | 2.16 (1.01-4.60) | 1.98 (1.17-3.36) | 2.10 (1.11-3.98) | |
| P for trend | .014 | .041 | |||||