Distribution of baseline characteristics according to tertiles of plasma levels of VWF
| . | Plasma VWF, % . | ||
|---|---|---|---|
| Tertile 1 (< 90.4) . | Tertile 2 (90.4-100.9) . | Tertile 3 (≥100.9) . | |
| N | 387 | 410 | 422 |
| Platelet count, mean ± SD, ×109/L | 251 ± 54 | 245 ± 53 | 238 ± 55 |
| MPV, mean ± SD, fL | 8.8 ± 0.9 | 8.8 ± 0.9 | 8.9 ± 1.1 |
| Age, mean ± SD, y | 57.0 ± 14.3 | 60.0 ± 13.7 | 63.4 ± 12.9 |
| Males | 47.8 (185) | 47.3 (194) | 45.7 (193) |
| BMI, mean ± SD, kg/m2 | 25.8 ± 3.9 | 26.6 ± 4.3 | 26.8 ± 4.6 |
| CRP, median (IQR), mg/L | 1.18 (0.65-2.23) | 1.14 (0.63-1.89) | 1.31 (0.65-2.33) |
| Hypertension* | 49.2 (190) | 56.5 (231) | 60.7 (256) |
| Cancer† | 5.0 (16) | 6.6 (21) | 5.4 (17) |
| CVD† | 12.9 (50) | 17.3 (71) | 18.0 (76) |
| Estrogen use‡ | 4.7 (18) | 5.1 (21) | 4.3 (18) |
| Smoking‡ | 41.1 (159) | 25.1 (103) | 26.1 (110) |
| . | Plasma VWF, % . | ||
|---|---|---|---|
| Tertile 1 (< 90.4) . | Tertile 2 (90.4-100.9) . | Tertile 3 (≥100.9) . | |
| N | 387 | 410 | 422 |
| Platelet count, mean ± SD, ×109/L | 251 ± 54 | 245 ± 53 | 238 ± 55 |
| MPV, mean ± SD, fL | 8.8 ± 0.9 | 8.8 ± 0.9 | 8.9 ± 1.1 |
| Age, mean ± SD, y | 57.0 ± 14.3 | 60.0 ± 13.7 | 63.4 ± 12.9 |
| Males | 47.8 (185) | 47.3 (194) | 45.7 (193) |
| BMI, mean ± SD, kg/m2 | 25.8 ± 3.9 | 26.6 ± 4.3 | 26.8 ± 4.6 |
| CRP, median (IQR), mg/L | 1.18 (0.65-2.23) | 1.14 (0.63-1.89) | 1.31 (0.65-2.33) |
| Hypertension* | 49.2 (190) | 56.5 (231) | 60.7 (256) |
| Cancer† | 5.0 (16) | 6.6 (21) | 5.4 (17) |
| CVD† | 12.9 (50) | 17.3 (71) | 18.0 (76) |
| Estrogen use‡ | 4.7 (18) | 5.1 (21) | 4.3 (18) |
| Smoking‡ | 41.1 (159) | 25.1 (103) | 26.1 (110) |
Unless otherwise noted, data are % (n).
CVD, cardiovascular disease; IQR, interquartile range; SD, standard deviation.
Defined as systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg.
Self-reported history of cancer or myocardial infarction, angina, or stroke at baseline.
Self-reported daily use of oral contraceptives or hormonal replacement therapy (estrogen use) or smoking of cigarettes or cigars (smoking).