Summary of disease entities and abbreviations
| Entity . | Abbreviation . | Cases, n . | Age (median y, range) . | Mutations (median) . |
|---|---|---|---|---|
| Myelodysplastic syndrome | MDS | 577 | 73 (23-93) | 2 |
| Myelodysplastic/myeloproliferative neoplasms, unclassifiable | MDS/MPN-U | 10 | 81 (77-85) | 4 |
| Myeloproliferative neoplasms | MPN | 306 | 68 (22-91) | 2 |
| Chronic myeloid leukemia | CML | 94 | 55 (16-85) | 0 |
| Atypical CML | aCML | 50 | 74 (50-92) | 4 |
| Chronic myelomonocytic leukemia | CMML | 24 | 75 (59-89) | 4 |
| Myeloid or lymphoid neoplasms associated with eosinophilia | MLN-eo | 36 | 51 (24-82) | 0 |
| Acute myeloid leukemia | AML | 675 | 68 (18-93) | 2 |
| Secondary acute myeloid leukemia | sAML | 16 | 70 (48-83) | 4 |
| Therapy-associated acute myeloid leukemia | tAML | 16 | 53 (33-73) | 1 |
| Acute undifferentiated leukemia | AUL | 24 | 74 (18-88) | 3 |
| Mixed phenotype acute leukemia | MPAL | 30 | 64 (19-89) | 2 |
| B-cell acute lymphoblastic leukemia | B-ALL | 224 | 54 (0.1-93) | 1 |
| T-cell acute lymphoblastic leukemia | T-ALL | 101 | 37 (11-91) | 2 |
| T-cell neoplasm | T-NHL | 33 | 62 (41-82) | 1 |
| NK cell neoplasm | NK | 40 | 68 (44-87) | 0 |
| B-cell neoplasm | B-NHL | 30 | 71 (46-83) | 1 |
| Burkitt’s lymphoma | BL | 20 | 69 (26-82) | 2 |
| Chronic lymphocytic leukemia | CLL | 263 | 67 (30-94) | 1 |
| Follicular lymphoma | FL | 63 | 54 (43-88) | 3 |
| Mantle cell lymphoma | MCL | 17 | 66 (29-81) | 1 |
| Lymphoplasmacytic lymphoma | LPL | 55 | 70 (42-88) | 2 |
| Hairy cell leukemia | HCL | 45 | 74 (35-86) | 1 |
| Hairy cell leukemia variant | HCL-v | 43 | 71 (42-81) | 1 |
| Monoclonal gammopathy of undetermined significance | MGUS | 12 | 61 (35-87) | 0 |
| Multiple myeloma | MM | 248 | 69 (26-91) | 1 |
| Persistent polyclonal B-cell lymphocytosis | PPBL | 29 | 45 (30-56) | 0 |
| Blastic plasmacytoid dendritic cell neoplasm | BPDCN | 15 | 74 (16-88) | 2 |
| Entity . | Abbreviation . | Cases, n . | Age (median y, range) . | Mutations (median) . |
|---|---|---|---|---|
| Myelodysplastic syndrome | MDS | 577 | 73 (23-93) | 2 |
| Myelodysplastic/myeloproliferative neoplasms, unclassifiable | MDS/MPN-U | 10 | 81 (77-85) | 4 |
| Myeloproliferative neoplasms | MPN | 306 | 68 (22-91) | 2 |
| Chronic myeloid leukemia | CML | 94 | 55 (16-85) | 0 |
| Atypical CML | aCML | 50 | 74 (50-92) | 4 |
| Chronic myelomonocytic leukemia | CMML | 24 | 75 (59-89) | 4 |
| Myeloid or lymphoid neoplasms associated with eosinophilia | MLN-eo | 36 | 51 (24-82) | 0 |
| Acute myeloid leukemia | AML | 675 | 68 (18-93) | 2 |
| Secondary acute myeloid leukemia | sAML | 16 | 70 (48-83) | 4 |
| Therapy-associated acute myeloid leukemia | tAML | 16 | 53 (33-73) | 1 |
| Acute undifferentiated leukemia | AUL | 24 | 74 (18-88) | 3 |
| Mixed phenotype acute leukemia | MPAL | 30 | 64 (19-89) | 2 |
| B-cell acute lymphoblastic leukemia | B-ALL | 224 | 54 (0.1-93) | 1 |
| T-cell acute lymphoblastic leukemia | T-ALL | 101 | 37 (11-91) | 2 |
| T-cell neoplasm | T-NHL | 33 | 62 (41-82) | 1 |
| NK cell neoplasm | NK | 40 | 68 (44-87) | 0 |
| B-cell neoplasm | B-NHL | 30 | 71 (46-83) | 1 |
| Burkitt’s lymphoma | BL | 20 | 69 (26-82) | 2 |
| Chronic lymphocytic leukemia | CLL | 263 | 67 (30-94) | 1 |
| Follicular lymphoma | FL | 63 | 54 (43-88) | 3 |
| Mantle cell lymphoma | MCL | 17 | 66 (29-81) | 1 |
| Lymphoplasmacytic lymphoma | LPL | 55 | 70 (42-88) | 2 |
| Hairy cell leukemia | HCL | 45 | 74 (35-86) | 1 |
| Hairy cell leukemia variant | HCL-v | 43 | 71 (42-81) | 1 |
| Monoclonal gammopathy of undetermined significance | MGUS | 12 | 61 (35-87) | 0 |
| Multiple myeloma | MM | 248 | 69 (26-91) | 1 |
| Persistent polyclonal B-cell lymphocytosis | PPBL | 29 | 45 (30-56) | 0 |
| Blastic plasmacytoid dendritic cell neoplasm | BPDCN | 15 | 74 (16-88) | 2 |
Entities highlighted in bold and comprising at least 50 cases were used for association analysis of patient age.